548486-23-3Relevant academic research and scientific papers
The influence of the long chain fatty acid on the antagonistic activities of Rhizobium sin-1 lipid A
Zhang, Yanghui,Wolfert, Margreet A.,Boons, Geert-Jan
, p. 4800 - 4812 (2008/03/14)
The lipid A from nitrogen-fixing bacterial species Rhizobium sin-1 is structurally unusual due to lack of phosphates and the presence of a 2-aminogluconolactone and a very long chain fatty acid, 27-hydroxyoctacosanoic acid (27OHC28:0), moiety. This struct
Preparation of a lipid A derivative that contains a 27-hydroxyoctacosanoic acid moiety
Santhanam, Balaji,Boons, Geert-Jan
, p. 3333 - 3336 (2007/10/03)
(Chemical Equation Presented) A general synthetic strategy for long-chain ω-1 hydroxy fatty acids has been developed, which employs as a key reaction step a cross metathesis between ω-unsaturated ester and 3-butene-2-ol. The resulting lipids were used for
Synthesis and biological evaluation of Rhizobium sin-1 lipid A derivatives
Demchenko, Alexei V.,Wolfert, Margreet A.,Santhanam, Balaji,Moore, James N.,Boons, Geert-Jan
, p. 6103 - 6112 (2007/10/03)
A highly convergent strategy for the synthesis of several derivatives of the lipid A of Rhizobium sin-1 has been developed. The approach employed the advanced intermediate 3-O-acetyl-6-O-(3-O-acetyl-4,6-O-benzylidene-2-deoxy-2-phthalimido- β-D-glucopyrano
