54863-88-6Relevant academic research and scientific papers
Selective Phosphorylation of Conjugated α-Enones at the Carbonyl Group, Catalyzed by Cyclohexylamine
Galkina,Saakyan,Cherkasov,Galkin,Cherkasov,Pudovik
, p. 344 - 348 (2007/10/03)
Reaction of dialkyl phosphites with benzalacetophenone (chalcone) and benzalacetone in the presence of cyclohexylamine as a catalyst is a convenient preparative method for selective phosphorylation of conjugated α, β-unsaturated carbonyl compounds at the carbonyl group. The kinetics of cyclohexylamine-catalyzed addition of dialkyl phosphites to cis- and trans-chalcones is studied, and factors are revealed that influence the reactivity of addends in this reaction.
Reaction of Dialkyl Phosphites with α-Enones. I. - Synthesis and Allylic Rearrangement of Dimethyl (1-Hydroxy-2-alkenyl)- and (1-Hydroxy-2-cycloalkenyl)phosphonates
Oehler, Elisabeth,Zbiral, Erich
, p. 175 - 184 (2007/10/02)
Various β,γ-unsaturated α-hydroxyphosphonates 3 are prepared in good yields by NaOCH3-catalyzed regioselective 1,2-addition of dimethyl phosphite to acyclic and cyclic α-enones at -35 deg C.On acid-catalyzed acetylation, the allylic α-hydroxyphosphonates
Reaction of benzalacetone with dimethylphosphorous acid
Arbuzov,Zoroastrova,Tudrii,Fuzhenkova
, p. 2541 - 2542 (2007/10/13)
1. In the presence of an equimolar amount of diethylamine or a catalytic amount of sodium methylate, dimethylphosphorous acid adds to the carbonyl group of benzalacetone to give the dimethyl ester of 4-phenyl-2-hydroxy-3-butenyl-2-phosphonic acid. 2. An equimolar amount of sodium methylate favors the formation of the dimethyl ester of 1-phenyl-2-acetylethylphosphonic acid.
