54867-60-6Relevant academic research and scientific papers
A new method for the facile synthesis of hydroxylated flavones by using allyl protection
Nawghare,Sakate,Lokhande
, p. 291 - 302 (2014/04/17)
The iodine-induced oxidative cyclization of 2′-hydroxychalcones provides a simple, highly efficient approach to various hydroxy flavones and analogues. This process is run under mild conditions, tolerates various functional groups, and provides hydroxy flavones in good to excellent yield. The allyl-protected acetophenones and benzaldehydes were smoothly deallylated under similar conditions.
Iodine catalyzed cascade synthesis of flavone derivatives from 2'-allyloxy-α,β-dibromochalcones
Nawghare, Beena R.,Gaikwad, Sunil V.,Raheem, Abdul,Lokhande, Pradeep D.
, p. 2284 - 2286 (2014/07/22)
Synthesis of flavones from 2'-allyloxy-α, β-dibromochalcones has been described. The iodine induced oxidative cyclization of 2'-allyloxy-α, β-dibromochalcones results into the formation of 3-bromoflavanones which ultimately gives flavones. Dehydrobromination of 3-bromoflavanone to give flavone is the preferred reaction over dehydrogenation.
Cytotoxic and antimicrobial activities of some synthetic flavones
Mostahar, Sohel,Alam, Sayed,Islam, Azizul
, p. 1478 - 1486 (2007/10/03)
Several flavones have been synthesized and their biocidal activity investigated along with their corresponding chalcones against some bacterial and fungal strains as well as brine shrimp nauplii. Compounds 13 and 14 show good antibacterial, antifungal and
