548738-96-1

Basic information

• Product Name: 4-Hydroxymethyl-2,4-dimethyl-3-[(E)-2-(2-propyl-[1,3]dioxan-5-yl)-vinyl]-cyclohex-2-enone
• Synonyms: 4-Hydroxymethyl-2,4-dimethyl-3-[(E)-2-(2-propyl-[1,3]dioxan-5-yl)-vinyl]-cyclohex-2-enone
• CAS NO: 548738-96-1
• Molecular Weight: 308.418
• Mol File: 548738-96-1.mol

Chemical Properties

• CAS DataBase Reference: 4-Hydroxymethyl-2,4-dimethyl-3-[(E)-2-(2-propyl-[1,3]dioxan-5-yl)-vinyl]-cyclohex-2-enone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydroxymethyl-2,4-dimethyl-3-[(E)-2-(2-propyl-[1,3]dioxan-5-yl)-vinyl]-cyclohex-2-enone(548738-96-1)
• EPA Substance Registry System: 4-Hydroxymethyl-2,4-dimethyl-3-[(E)-2-(2-propyl-[1,3]dioxan-5-yl)-vinyl]-cyclohex-2-enone(548738-96-1)

Safety Data

• Hazardous Substances Data: 548738-96-1(Hazardous Substances Data)

Upstream product

• 355423-25-5 2-(2-propyl-[1,3]dioxan-5-ylmethylsulfanyl)-benzothiazole 
• 355423-21-1 2-propyl-[1,3]dioxane-5-carboxylic acid ethyl ester 
• 355423-71-1 methanesulfonic acid 2-propyl-[1,3]dioxan-5-ylmethyl ester 
• 4740-64-1 (2-propyl-[1,3]dioxan-5-yl)-methanol 
• 364618-38-2 1,3-Dimethyl-4-oxo-2-[(E)-2-(2-propyl-[1,3]dioxan-5-yl)-vinyl]-cyclohex-2-enecarboxylic acid methyl ester 
• 355423-15-3 2-(2-propyl-[1,3]dioxan-5-ylmethanesulfonyl)-benzothiazole 
• 69841-90-3 4,8-dimethyl-1,5-dioxo-3-hydroxy-2-oxabicyclo<4.3.0>non-4(9)-ene 
• 548738-94-9 4-Hydroxymethyl-2,4-dimethyl-3-[(E)-2-(2-propyl-[1,3]dioxan-5-yl)-vinyl]-cyclohex-2-enol 

Relevant articles and documents

Detours en route to a total synthesis of (+)-cassiol

A synthesis of the antiulcerogenic compound (+)-cassiol 1b has been achieved in 43% yield starting with lactol (S)-2 and sulfone 26. This short and efficient synthesis features the one-pot Julia olefination reaction of the sodium anion of (S)-2 with 26, through the key intermediate (-)-9. This synthesis has been developed as a result of exploratory experiments including different olefination reactions on 2. An attempt to synthesize the intermediate 9 by an intramolecular aldol condensation approach of the open chain precursor 4 is also described.