54874-12-3 Usage
Uses
Used in Organic Synthesis:
1-(4-BROMOPHENYL)-5-CHLORO-1-OXOPENTANE is used as a building block in the synthesis of more complex organic molecules. Its unique structure, featuring a bromine and chlorine atom, allows for further functionalization and the creation of a diverse range of compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-(4-BROMOPHENYL)-5-CHLORO-1-OXOPENTANE is used as an intermediate in the development of new drugs. Its structural features can be exploited to design and synthesize novel therapeutic agents with potential applications in various medical fields.
Used in Research:
1-(4-BROMOPHENYL)-5-CHLORO-1-OXOPENTANE is also employed as a research tool in chemical and biological studies. Its unique properties make it a valuable compound for investigating various chemical reactions and understanding the underlying mechanisms involved.
Check Digit Verification of cas no
The CAS Registry Mumber 54874-12-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,8,7 and 4 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 54874-12:
(7*5)+(6*4)+(5*8)+(4*7)+(3*4)+(2*1)+(1*2)=143
143 % 10 = 3
So 54874-12-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H12BrClO/c12-10-6-4-9(5-7-10)11(14)3-1-2-8-13/h4-7H,1-3,8H2
54874-12-3Relevant academic research and scientific papers
Regioselective Synthesis of Carbonyl-Containing Alkyl Chlorides via Silver-Catalyzed Ring-Opening Chlorination of Cycloalkanols
Huang, Feng-Qing,Xie, Jian,Sun, Jian-Guo,Wang, Yue-Wei,Dong, Xin,Qi, Lian-Wen,Zhang, Bo
supporting information, p. 684 - 687 (2016/03/01)
A novel and regioselective approach to carbonyl-containing alkyl chlorides via silver-catalyzed ring-opening chlorination of cycloalkanols is reported. Concurrent C(sp3)-C(sp3) bond cleavage and C(sp3)-Cl bond formation efficiently occur with good yields under mild conditions, and the chlorinated products are readily transformed into other useful synthetic intermediates and drugs. The reaction features complete regioselectivity, high efficiency, and excellent practicality. (Chemical Equation Presented).
The search of novel inhibitors of HIV-1 Integrase among 5-(4-Halogenophenyl)-5-oxopentyl derivatives of nucleic bases
Komissarov,Knyazhanskaya,Atrokhova,Gottikh,Kritzyn
, p. 532 - 540 (2015/12/01)
New nucleic base derivatives were obtained by alkylation of uracil, thymine, cytosine, adenine, 6-chloropurine, and 2-Amino-6-chloropurine with 5-chloro-1-(4-halogenophenyl)-1-pentanones, and their physical and chemical properties were studied. The influe
