54874-33-8

Upstream product

• 54874-32-7 (E)-1,4-dimethyl-4-nitrocyclohexa-2,5-dienyl acetate 
• 62622-59-7 4-methyl-4-nitrocyclohexa-2,5-dien-1-one 
• 917-54-4 methyllithium 

Downstream Products

• 54874-32-7 (E)-1,4-dimethyl-4-nitrocyclohexa-2,5-dienyl acetate 
• 90554-26-0 trans-3,6-Dimethoxy-3,6-dimethyl-1,4-cyclohexadiene 
• 54874-35-0 (E)-1,4-dimethyl-4-nitrocyclohexa-2,5-dienyl methyl ether 
• 95-87-4 2,5-Dimethylphenol 
• 105-67-9 2,4-Xylenol 
• 89-58-7 mononitro-p-xylene 
• 104824-12-6 trans-1,4-dimethylcyclohexa-2,5-diene-1,4-diol 
• 104824-13-7 (Z)-1,4-dimethylcyclohexa-2,5-diene-1,4-diol 
• 74894-53-4 anti-4-methoxy-1,4-dimethyl-2,5-cyclohexadienol 
• 74894-52-3 (Z)-4-methoxy-1,4-dimethylcyclohexa-2,5-dienol 

Relevant academic research and scientific papers

Formation of 4-Nitrocyclohexa-2,5-dienols by Addition of Organolithium Reagents to 4-Alkyl-4-nitrocyclohexa-2,5-dienones

Addition of methyllithium to 4-alkyl-4-nitrocyclohexa-2,5-dienones 1a-d (alkyl = Me, Et, i-Pr, t-Bu), to 2,6-dichloro- and 2,6-dibromo-4-methyl-4-nitrocyclohexa-2,5-dienone, and to 4a-nitro-2-oxo-2,4a,5,6,7,8-hexahydronaphthalene gives the corresponding dienols 2a-d, 4e and 4f, and 7g, generally as a pair of diastereomers.Addition of methyl lithioacetate to the same substrates gives dienols 8a-d, 5e and 5f, and 7h.Addition of substituted methyllithiums (XCH2Li, X = CN, CONH2, CONMe2, COMe, SMe, SPh, SOMe, SO2Me, SiMe3, PSMePh, PSPh2), 2-lithio-1,3-dithiane, or lithium phenylacetylide to 1a gives the dienols 9i-u.

Ipso nitration. XXII. The stereochemistry of 1,4-dimethyl-4-nitrocyclohexa-2,5-dienols and their acetates and methyl ethers

The higher melting isomer of 1,4-dimethyl-4-nitrocyclohexa-2,5-dienol has the (E)-configuration.The stereospecific interconversion of the dienols and the corresponding acetates and the stereospecific conversion of dienols to methyl ethers allow the assign