548777-91-9Relevant academic research and scientific papers
The Length and Flexibility of the 2-Substituent of 9-Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2AAdenosine Receptor
Thomas, Ajiroghene,Buccioni, Michela,Dal Ben, Diego,Lambertucci, Catia,Marucci, Gabriella,Santinelli, Claudia,Spinaci, Andrea,Kachler, Sonja,Klotz, Karl-Norbert,Volpini, Rosaria
, p. 1829 - 1839 (2016)
The A2Aadenosine receptor (A2AAR) is a key target for the development of pharmacological tools for the treatment of central nervous system disorders. Previous works have demonstrated that the insertion of substituents at various posi
A2A adenosine receptor antagonists
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, (2008/06/13)
Disclosed are novel A2A adenosine receptor antagonists, useful for treating various disease states, for example cardiovascular disorders, including tissue damage due to ischemia, CNS diseases, including Parkinson's disease, depression, and the
