548780-40-1Relevant academic research and scientific papers
Asymmetric synthesis of α-amino allyl, benzyl, and propargyl silanes by metalation and rearrangement
Sieburth, Scott McN.,O'Hare, Heather K.,Xu, Jiayi,Chen, Yanping,Liu, Guodong
, p. 1859 - 1861 (2007/10/03)
(Matrix presented) Metalation of a Boc-protected N-silylamine α to nitrogen results in migration of the silicon from nitrogen to carbon (reverse aza-Brook rearrangement), yielding an α-amino silane. The Boc group acts initially as a metalation-directing g
