548783-11-5Relevant academic research and scientific papers
Synthesis of Hsp90 inhibitor dimers as potential antitumor agents
Muranaka, Kazuhiro,Sano, Akiko,Ichikawa, Satoshi,Matsuda, Akira
, p. 5862 - 5870 (2008/12/21)
Structure-based drug design was used to systematically synthesize PU3-dimers. The cytotoxicity of PU3 dimers 6 against breast cancer cell lines was evaluated, and their potency increased as the length of the bridging linker increased. Among the compounds
