548794-88-3Relevant academic research and scientific papers
Cycloisomerization – a straightforward way to benzo[h]quinolines and benzo[c]acridines
Shestakov, Aleksandr N.,Pankova, Alena S.,Kuznetsov, Mikhail A.
, p. 1103 - 1113 (2017/12/08)
[Figure not available: see fulltext.] Cycloisomerization of 3-alkynyl-2-arylpyridines and quinolines offers a straightforward approach to benzo[h]quinolines and benzo[c]-acridines. Substituent at the triple bond governs a choice between transition metal or Br?nsted acid catalysis. A direct electrophilic activation by trifluoromethanesulfonic acid induces an almost quantitative cyclization of the o-aryl(phenylethynyl) fragment. PtCl2 efficiently catalyzes cyclization of 2-aryl-3-ethynylhetarenes.
Metal free TBHP-promoted intramolecular carbonylation of arenes: Via radical cross-dehydrogenative coupling: Synthesis of indenoquinolinones, 4-azafluorenones and fluorenones
Mishra, Kalpana,Pandey, Ashok Kumar,Singh, Jay Bahadur,Singh, Radhey M.
, p. 6328 - 6336 (2016/07/11)
A metal-free, TBHP-promoted economical route is developed via the sp2 C-H bond functionalization strategy for the synthesis of indenoquinolinones, 4-azafluorenones and fluorenones. Reactions provided excellent yield of the products under mild conditions. We have successfully synthesized 11H-indeno[1,2-b]quinolin-11-one, an antibacterial agent, in excellent yields.
Synthesis of pyrrolo[3,4-c]quinolines by 1,5-electrocyclisation of non-stabilised azomethine ylides
Nyerges, Miklós,Pintér, áron,Virányi, Andrea,Blaskó, Gábor,Toke, László
, p. 8199 - 8205 (2007/10/03)
A new route to the pyrrolo[3,4-c]quinoline ring system has been developed via the 1,5-dipolar electrocyclisation reactions of azomethine ylides derived from easily available 3-formylquinoline derivatives. The intermediacy of azomethine ylides was shown by the trapping of the proposed dipoles with N-phenylmaleimide.
Synthesis of pyrrolo[3,4-c]quinolines by 1,5-electrocyclisation of non-stabilised azomethine ylides
Pintér, áron,Nyerges, Miklós,Virányi, Andrea,Toke, László
, p. 2343 - 2346 (2007/10/03)
A new route to the pyrrolo[3,4-c]quinoline ring system has been developed via the 1,5-dipolar electrocyclisation reactions of azomethine ylides derived from easily available 3-formylquinoline derivatives. The intermediacy of azomethine ylides was shown by the trapping of the proposed dipoles with N-phenylmaleimide.
