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Downstream Products

• 107734-06-5 N-tosyl-2-phenylindole 
• 727416-65-1 3-phenyl-1-(toluene-4-sulfonyl)-1H-indole 

Relevant academic research and scientific papers

The cooperative FeCl3/DDQ system for the regioselective synthesis of 3-arylindoles from β-monosubstituted 2-alkenylanilines

A highly regioselective synthesis of 3-arylindoles by using the cooperative FeCl3/DDQ system has been developed. This new protocol represents an attractive route for the synthesis of 3-arylindoles from readily accessible non-indole precursors, β-aryl-substituted 2-styrylanilines, using an inexpensive catalyst and oxidant. Noteworthy is the unique synergetic and synergistic effect of FeCl3 and DDQ on the 1,2-aryl migratory process.

Bi(OTf)3-mediated intramolecular hydroamination of 2-aminostilbenes for the synthesis of 2-arylindolines

An efficient Bi(OTf)3-mediated intramolecular hydroamination of 2-aminostilbenes for the synthesis of various 2-arylindolines has been developed. Various advantages using Bi(OTf)3as a catalyst, such as the operationally easy, simple, and safe procedure, good to excellent chemical yields, and the use of relatively low catalyst loading are noteworthy.

Heptadecafluorooctanesulfonic acid (C8F17SO3H) catalyzed intramolecular hydroamination of olefinic sulfonamides in fluorous biphase system (FBS)

A practical, efficient, and environmentally benign intramolecular hydroamination of olefinic sulfonamides was carried out in fluorous biphase system (FBS) using commercially available heptadecafluorooctanesulfonic acid (C8F17SO3

Synthesis of indolines and quinoline Via cyclization of N-arylsulfonyl-2-allylanilines catalyzed by bronsted acid

N-Arylsulfonyl-2-allylanilines underwent the intramolecular hydroamination to produce indolines or quinoline in the presence of catalytic amount of triflic acid with good yield. The scope of the reaction was extended to other N-protected aminoalkenes.