54888-60-7

Basic information

• Product Name: 1H-Indole, 2,3-dihydro-2-(4-methoxyphenyl)-
• CAS NO: 54888-60-7
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• Mol File: 54888-60-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 2,3-dihydro-2-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 2,3-dihydro-2-(4-methoxyphenyl)-(54888-60-7)
• EPA Substance Registry System: 1H-Indole, 2,3-dihydro-2-(4-methoxyphenyl)-(54888-60-7)

Safety Data

• Hazardous Substances Data: 54888-60-7(Hazardous Substances Data)

Upstream product

• 1181455-14-0 C₁₅H₁₅N₃O 
• 24310-46-1 4-methoxyacetophenone phenylhydrazone 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 5784-95-2 2-(4-methoxyphenyl)-1H-indole 
• 42116-43-8 tert-butyl 2-phenylhydrazine-1-carboxylate 
• 92491-22-0 tert-butyl 2-phenyldiazene-1-carboxylate 

Downstream Products

• 54888-64-1 2-(4-methoxyphenethyl)aniline 
• 25410-78-0 2-(4-methoxyphenyl)-3-oxo-3H-indole 1-oxide 
• 54888-68-5 C₂₂H₂₂N₂O₃S 
• 1143570-97-1 (-)-(S)-2-(4-methoxyphenyl)indoline 

Relevant articles and documents

Kinetic resolution of indolines through reductive amination of aldehydes by chiral Br?nsted acid

We have developed a highly efficient and practical strategy for the kinetic resolution of indoline derivatives, involving a chiral Br?nsted acid-catalyzed iminium ion formation and asymmetric transfer hydrogenation cascade process. The kinetic resolution allows the synthesis of 2-substituted N-benzylindolines in good yields with moderate to excellent enantioselectivities.

Rhodium(III)-catalyzed cyclative capture approach to diverse 1-aminoindoline derivatives at room temperature

A RhIII-catalyzed C-H activation/cyclative capture approach, involving a nucleophilic addition of C(sp3)-Rh species to polarized double bonds is reported. This constitutes the first intermolecular catalytic method to directly access 1-aminoindolines with a broad substituent scope under mild conditions.

Chiral phosphoric acid-catalyzed oxidative kinetic resolution of indolines based on transfer hydrogenation to imines

The oxidative kinetic resolution of 2-substituted indoline derivatives was achieved by hydrogen transfer to imines by means of a chiral phosphoric acid catalyst. The oxidative kinetic resolution was applicable to racemic alkyl- or aryl-substituted indolines, and the remaining indolines were obtained in good yields with excellent enantioselectivities.