5492-70-6

Upstream product

• 25131-60-6 2-phenacylisoquinolinium bromide 
• 586-96-9 Nitrosobenzene 
• 5667-47-0 phenacyldimethylsulfonium bromide 
• 19320-74-2 Se-phenacyldimethylselenonium bromide 
• 5165-33-3 2-hydroxy-2-(N-hydroxy-anilino)-1-phenyl-ethanone 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 16883-69-5 N-phenacylpyridinium bromide 
• 70-11-1 α-bromoacetophenone 
• 87221-63-4 C₁₇H₂₁NO₂Si 

Downstream Products

• 5165-33-3 2-hydroxy-2-(N-hydroxy-anilino)-1-phenyl-ethanone 
• 7397-17-3 phenylglyoxal oxazone 
• 91118-37-5 phenyl-glyoxal-bis-phenylimine 
• 64258-40-8 1-phenyl-glyoxal-1-(phenyl-seqcis-hydrazone)-2-(phenyl-seqtrans-hydrazone) 
• 15823-87-7 phenylglyoxal-2-(Z)-phenylhydrazone 
• 15808-13-6 n-(1-phenyl)-N'-(2-phenyl-2-oxo-1-ethylidene)hydrazine 
• 68790-73-8 phenyl-(2-phenyl-5-pyridin-2-yl-isoxazolidin-3-yl)-methanone 
• 72459-12-2 (5-ethyl-2-phenyl-(3ar,6ac)-2,3,3a,6a-tetrahydro-furo[2,3-d]isoxazol-3c-yl)-phenyl-methanone 
• 70263-56-8 2-phenyl-3-benzoyl-5-phenoxyisoxazolidine 
• 22269-78-9 (2,5-diphenylisoxazolidin-3-yl)(phenyl)methanone 
• 72502-78-4 3-benzoyl-8,8-dimethyl-2,5,5-triphenyl-2,3,5,8-tetrahydro-8λ⁵-[1,2]azaphospholo[2,1-b][1,3,5,2]oxadiazaphosphole-6,7-dicarboxylic acid dimethyl ester 
• 22269-76-7 phenyl-(2-phenyl-octahydro-4,7-methano-benzo[d]isoxazol-3-yl)-methanone 
• 70263-54-6 [5-(4-chloro-phenyl)-2-phenyl-isoxazolidin-3-yl]-phenyl-methanone 
• 70263-55-7 [5-(4-methoxy-phenyl)-2-phenyl-isoxazolidin-3-yl]-phenyl-methanone 

Relevant academic research and scientific papers

Endo-selective asymmetric inverse electron-demand 1,3-dipolar cycloaddition reaction of nitrones

In the presence of a catalytic amount of the optically active cobalt(III) hexafluoroantimonate, the inverse electron-demand 1,3-dipolar cycloaddition reaction of dihydrofuran with nitrones bearing an electron-withdrawing group effectively proceeded to aff

The reaction of α- and ω-methylenelactams with nitrones. Influence of electronic and geometric factors on the stereoselectivity of their 1,3-dipolar cycloaddition

Various four to six-membered ring α- and ω-methylenelactams 1-5 were reacted with nitrones 6 and afforded good yields of spiroadducts 7-12 through a regiospecific [3 + 2] cycloaddition. Owing to the creation of at least two new asymmetric centres, mixtures of diastereoisomers were usually obtained whose structures were established by two-dimensional NOESY experiments or X-ray crystallography. Among the dipolarophiles, 3-methyleneazetidin-2-ones 1 yielded adducts with a very high stereoselectivity. A similar behaviour was also observed with α-benzoylnitrone 6a as a 1,3-dipole. Electronic and geometric interactions of the reagents 1-5 and 6 in the course of the cycloaddition process were discussed in order to account for the experimental stereochemical outcomes.

On the Stereoselectivity of Nitrone Addition to α-Diphenylphosphinoylalkenes

The title reaction was investigated for both achiral and α-chiral alkenes 1-3, and for cyclic and acyclic nitrones 4 and 8.In each case, addition to allyldiphenylphosphine oxide 1 gave a single isoxazolidine product.The configurations of these isoxazolidi

SELENONIUM MONOKETOYLIDES IN THE SYNTHESIS OF 4- and 5-SPIROISOXAZOLIDINES

Preparative methods have been developed for the synthesis of 4- and 5-spiroisoxazolidines by the reaction of C-benzoyl-N-phenylnitrone with methylenecycloalkanes and 2-arylmethyleneindanediones.The reaction of the nitrone with methylenecycloalkanes proceeds with steric specifity.Two epimeric isoxazolidines are formed in the presence of a substituent in the phenyl ring of the arylmethyleneindanedione.