54920-86-4Relevant articles and documents
Benzothiopyranoindazoles, a new class of chromophore modified anthracenedione anticancer agents. Synthesis and activity against murine leukemias
Hollis Showalter,Angelo,Berman,Kanter,Ortwine,Ross-Kesten,Sercel,Turner,Werbel,Worth,Elslager,Leopold,Shillis
, p. 1527 - 1539 (2007/10/02)
The synthesis of the benzothiopyranoindazoles (3), a new class of chromophore modified anthracenediones related to mitoxantrone (1), is described. In this structural class the quinone moiety, which is believed to be responsible for the cardiotoxicity of t