54921-75-4

Basic information

• Product Name: 1,1′-[(3-nitrophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)
• Synonyms: 1,1′-[(3-nitrophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)
• CAS NO: 54921-75-4
• Molecular Weight: 469.491
• Mol File: 54921-75-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,1′-[(3-nitrophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1′-[(3-nitrophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)(54921-75-4)
• EPA Substance Registry System: 1,1′-[(3-nitrophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)(54921-75-4)

Safety Data

• Hazardous Substances Data: 54921-75-4(Hazardous Substances Data)

Upstream product

• 619-25-0 3-Nitrobenzyl alcohol 
• 135-77-3 1,2,4-trimethoxy-benzene 
• 99-61-6 3-nitro-benzaldehyde 

Relevant articles and documents

Niobium Pentachloride Mediated (Hetero)aromatic Aldehyde Friedel-Crafts Hydroxyalkylation with Arenes: An Efficient Strategy to Synthesize Triarylmethanes

Niobium pentachloride is an efficient and useful Lewis acid to conduct Friedel-Crafts hydroxyalkylation between arenes and (hetero)aromatic aldehydes, to generate triarylmethanes. This practical methodology offers several advantages, such as short reaction time, mild experimental conditions, and excellent yields.

Novel and highly efficient one pot protocol for the synthesis of diversely functionalized triarylmethanes

An efficient, convenient, and novel one pot approach is described for the synthesis of triarylmethanes by in situ oxidation of benzylalcohols followed by the Friedel-Crafts alkylation of di/trimethoxybenzenes in the presence of BF3·OEt2. The generality of the present method is strengthened by screening a variety of aromatic, aliphatic, and heteroaromatic alcohols with methoxy arenes. Shorter reaction time, mild reaction condition, good yields, and wide scope of substrates are the significant features of this protocol.