54949-15-4 Usage
Uses
Used in Pharmaceutical Industry:
4,6-DICHLORO-2H-1-BENZOTHIINE-3-CARBALDEHYDE is used as a key intermediate in the synthesis of various pharmaceutical compounds for its ability to contribute to the development of new drugs and enhance the properties of existing ones.
Used in Agrochemical Industry:
In the agrochemical sector, 4,6-DICHLORO-2H-1-BENZOTHIINE-3-CARBALDEHYDE is employed as a precursor in the production of agrochemicals, contributing to the formulation of pesticides and other agricultural chemicals that protect crops and enhance yield.
Used in Organic Synthesis:
4,6-DICHLORO-2H-1-BENZOTHIINE-3-CARBALDEHYDE is used as an intermediate in organic synthesis for its role in creating a variety of organic compounds, which can be further utilized in different chemical and industrial applications.
Used in Research and Development:
4,6-DICHLORO-2H-1-BENZOTHIINE-3-CARBALDEHYDE is also utilized in research and development settings, where it aids scientists in exploring new chemical reactions and developing innovative applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 54949-15-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,9,4 and 9 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 54949-15:
(7*5)+(6*4)+(5*9)+(4*4)+(3*9)+(2*1)+(1*5)=154
154 % 10 = 4
So 54949-15-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H6Cl2OS/c11-7-1-2-9-8(3-7)10(12)6(4-13)5-14-9/h1-4H,5H2
54949-15-4Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of 4-chloro-2H-thiochromenes featuring nitrogen-containing side chains as potent antifungal agents
Wang, Dan-Jiao,Hou, Zhuang,Xu, Hang,An, Ran,Su, Xin,Guo, Chun
, p. 3574 - 3578 (2018/10/15)
A series of 4-chloro-2H-thiochromenes featuring nitrogen-containing side chains were designed, synthesized and tested in vitro for their antifungal activities. The results of preliminary antifungal tests showed that most target compounds exhibited good inhibitory activities against Candida albicans, Cryptococcus neoformans, Candida tropicalis. Notably, compounds 10e and 10y showed most potent activity in vitro against a variety of fungal pathogens with low MICs. Meanwhile, low cytotoxicity on mammalian cells has been observed for compounds 10e and 10y in the tested concentrations by the MTT assay. Therefore, the 4-chloro-2H-thiochromenes with nitrogen-containing groups provide new lead structures in the search for novel antifungal agents.
SUBSTITUTED SULFONE-CONTAINING TRICYCLIC COMPOUNDS AND USES THEREOF
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Page/Page column 32; 33, (2014/05/24)
The present invention relates to substituted sulfone-containing tricyclic compounds and analogues thereof which inhibit Bak-mediated apoptosis. The invention further relates to pharmaceutical compositions comprising a compound of the present invention and to methods of inhibiting a Bak-mediated apoptotic pathway and Bak-mediated apoptosis in a cell.
