549494-75-9

Upstream product

• 38059-09-5 bis(hydroxymethylphenyl)sulfide 
• 40138-16-7 2-formylbenzene boronic acid 
• 139-66-2 diphenyl sulfide 
• 26260-02-6 2-iodobenzaldehyde 
• 94-41-7 benzalacetophenone 
• 6630-33-7 ortho-bromobenzaldehyde 
• 147-93-3 Thiosalicylic acid 
• 4521-31-7 o-hydroxymethyl thiophenol 
• 63744-05-8 2-(2-hydroxymethylphenylthio)benzaldehyde 
• 89-98-5 2-chloro-benzaldehyde 

Downstream Products

• 1443212-52-9 C₁₄H₁₀O₃S 

Relevant academic research and scientific papers

A new concise strategy for synthesis of dibenzo[b,f]thiepins and related fused symmetrical thiepin derivatives

(Chemical Equation Presented) A new strategy for preparation of dibenzo[b,f]thiepins and related fused systems in good overall yields is described, featuring ortho-metalation of aromatic or heterocyclic aldehyde acetals followed by treatment with bis(phen

Domino Synthesis of Thiochromenes through Cu-Catalyzed Incorporation of Sulfur Using Xanthate Surrogate

An efficient domino reaction has been developed for the synthesis of thiochromenes through Cu-catalyzed in situ incorporation of sulfur. This domino method avoids the use of less accessible and unpleasant arenethiols as starting materials, instead utilize

N-Heterocyclic carbene (NHC)-catalyzed intramolecular benzoin condensation-oxidation

NHC-Catalyzed intramolecular benzoin condensation-oxidation is developed for the expedient synthesis of diverse cyclic 1,2-diketones incorporated in dibenzo-fused seven-membered heterocycles in good to excellent yields, under ambient conditions. The prese

A novel and efficient method for the direct synthesis of pyrrolyl or indolyl substituted 9,10-dihydrophenanthren-9-ol analogues

A novel domino intramolecular [3+2] cycloaddtion and ring-opening aromatization process has been successfully developed for the efficient direct synthesis of pyrrolyl or indolyl substituted 9,10-dihydrophenanthren-9-ol analogues. And 1-(phenanthren-9-yl)-

Method for synthesis of double heterocyclic compound containing sulfur and nitrogen

The invention discloses a method forsynthesis of a double heterocyclic compound containing sulfur and nitrogen, and belongs to the technical field of organic chemistry. An indolecompound1, an o-bromobenzaldehydecompound2 andelemental sulfur are used as ra

Histidine-functionalized chitosan-Cu(II) complex: A novel and green heterogeneous nanocatalyst for two and three component C-S coupling reactions

Using a fixing Cu2+ NP reaction on histidine modified chitosan, a novel applicable matrix was successfully prepared and investigated as a heterogeneous nanocatalyst for preparing diaryl sulfides and aryl benzyl thioethers. The Cu(ii)-his@CS nanocatalyst was characterized by FT-IR, CHN, XRD, FE-SEM, TEM, EDX, ICP-AES and TG analysis. This novel copper nanocatalyst was used for two and three component C-S coupling reactions of different aryl halides. The nanocatalyst showed high catalytic activity and reusability in both reactions.

Synthesis and structural characterization of Rh(III) complexes containing diamino ligands of types {D(C6H4NH2)2} and {D(C6H4CH2NHEt)2} (D?=?O, S) bearing different spacers

The reaction of the diamino ligands of general formula {D(C6H4NH2)2} [D?=?O (L1); S (L2)] and {D(C6H4CH2NHEt)2} [D?=?O (L3); S (L4)] with RhCl3·3H2O yielded neutral coordination complexes [RhIII(Ln)Cl3] [n?=?1 (1); n?=?2 (2); n?=?3 (4); n?=?4 (5)]. Compound 1 in N,N-dimethylformamide solution promoted the formation of the neutral complex [RhIII(L1)(dmf)Cl3] (3). A zwitterionic complex [RhIII(HL4)Cl4] (6) was obtained from the reaction of L4with RhCl3·3H2O as a minor compound. All complexes were characterized in solution by NMR and by vibrational spectroscopy in solid state. Crystal structures of the chlorohydrates [H2L3]Cl2·H2O, [H2L4]Cl2, and the complexes 2–6 were identified by X-ray diffraction studies. Molecular structures of the complexes revealed different coordination patterns of the diamino ligands Lnas well as the formation of chelate rings of five-, six-, and eight members. The presence of N–H groups in the title compounds enhanced the formation of hydrogen bond networks that were analyzed on the basis of a graph set analysis approach, displaying rings at the first to third level.

Diarylation of chalcogen elements using arylboronic acids via copper- or palladium-catalyzed oxidative coupling

Transition metal-catalyzed diarylations of sulfur, selenium and tellurium were achieved using arylboronic acids in air. A copper-catalyzed reaction of sulfur or selenium efficiently yielded numerous symmetrical diaryl sulfides or selenides in the presence of NH4BF4. However, the diarylation of tellurium was not possible using this method, and required a palladium catalyst in the presence of KI and air for the reaction to proceed.

Efficient catalysts for asymmetric Mannich reactions

Efficient chiral catalysts for direct asymmetric three-component Mannich reactions of ketones, aldehydes and an amine (p-anisidine) have been developed. The corresponding β-amino carbonyl compounds (Mannich adducts) were obtained in good chemical yields a

Synthesis and biological activity of sulfur-containing aryl-aldehyde Schiff bases.

A series of chemically modified aryl-aldehyde Schiff bases has been synthesized and tested for their antioxidant activity and radiation protection. We observed that disulfide-containing aryl-aldehyde Schiff base 6c exhibited potent free radical scavenging