549501-67-9Relevant academic research and scientific papers
A PHARMACEUTICAL COMPOSITION COMPRISING A SUBSTITUTED PHENYLPROPIONIC ACID AS A FREE ACID AND AS TERT-BUTYL AMINE SALT THEREOF
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Page/Page column 22-23; 26-27, (2008/06/13)
A pharmaceutical composition comprising a compound of formula I wherein n is 1 or 2, R1 represents hydrogen, chloro, trifluoromethyl or trifluoromethoxy, R2 represents hydrogen or fluoro and R3 represents a C2-6alkyl group, wherein the compound of formula (I) is present in the composition as a free acid and as a tert-butyl amine salt thereof.
TRI (HYDROXYMETHYL) METHYLAMINE SALT OR AN ETHANOL AMINE SALT OF (2S) -2-ETHOXY-3- (4-{2- [HEXYL (2- PHENYLETHYL) AMINO] - 2 -OXOETHOXY} PHENYL) PROPANOIC ACID
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Page/Page column 23, (2010/11/08)
The invention relates to a compound selected from one or more of the following: a tris (hydroxymethyl) methylamine salt of (2S)-2- ethoxy-3-(4-{2- [hexyl (2-phenylethyl) amino]-2- oxoethoxy} phenyl) propanoic acid; an ethanol amine salt of (2S)-2-ethoxy-3- (4-{2-[hexyl (2-phenylethyl) amino]-2-oxoethoxy} phenyl) propanoic acid; or a pharmaeutical composition comprising the compound.
THERAPEUTIC AGENTS
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Page 22, (2008/06/13)
The present invention provides the S enantiomer of a compound of formula (I) wherein R1 represents chloro, trifluoromethyl or trifluoromethoxy, R2 represents H or fluoro and R3 represents a C2-4alkyl group as well as pharmaceutically acceptable salts, solvates and prodrugs thereof, to processes for preparing such compounds, to their the utility in treating clinical conditions including lipid disorders (dyslipidemias) whether or not associated with insulin resistance, to methods for their therapeutic use and to pharmaceutical compositions containing them.
PHARMACEUTICALLY USEFUL SALTS OF CARBOXYLIC ACID DERIVATES
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Page/Page column 23-24, (2008/06/13)
A calcium or a magnesium salt of (2S)-2-ethoxy-3-(4-{2[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid.
PHARMACEUTICALLY USEFUL SALTS OF CARBOXYLIC ACID DERIVATES
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Page 24, (2010/02/09)
A compound selected from one or more of the following: a ( 1R,2S)-2-hydroxyindan-1-amine salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid; an L-arginine salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino-2-oxoethoxyphenyl)propanoic acid; a tert-butylamine salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino-2-oxoethoxyphenyl)propanoic acid; a choline salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid; an adamantylamine salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid; a N-benzyl-2-phenylethanaminium salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid; aN-benzyl-2-(benzylamino) ethanaminium salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid; or a tris(hydroxymethyl)methylamine salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid.
