549503-57-3

Upstream product

• 19009-39-3 N,N-diisopropylcarbamoyl chloride 
• 50919-06-7 2-(2-fluorophenyl)ethanol 
• 451-82-1 (2-fluorophenyl)acetic acid 

Downstream Products

• 549503-58-4 2-(2-fluorophenyl)-1-methylethyl diisopropylcarbamate 

Relevant academic research and scientific papers

Synthesis of Novel Chiral Benzophospholanes and Their Application in Asymmetric Hydrogenation

A new class of chiral ligands bearing one or two benzophospholanes was developed for the purpose of Ru-catalyzed asymmetric hydrogenation. Although results of the Ru catalysis remain insufficient so far, 1,2-bis(2-isopropyl-2,3- dihydro-1H-phosphindol-1-yl)benzene (iPr-BeePHOS: 2b) has been found to provide high enantioselectivity in the Rh-catalyzed asymmetric hydrogenation of an enamide.

Novel phosphine compound, transition metal complex containing the same phosphine compound as ligand and asymmetric synthesis catalyst containing the complex

A phosphine compound of formula (1) and a phosphine compound of formula (2) a transition metal complex having the phosphine compound as a ligand and a catalyst for asymmetric hydrogenation including the transition metal complex.