549505-36-4 Usage
Uses
Used in Organic Synthesis:
[1,1-Biphenyl]-2,4-diol,3-iodo-(9CI) is used as a building block in organic synthesis for the creation of more complex molecules. Its unique structure allows it to participate in various chemical reactions, making it a valuable component in the synthesis of a wide range of compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, [1,1-Biphenyl]-2,4-diol,3-iodo-(9CI) is used as a ligand in metal-catalyzed cross-coupling reactions. These reactions are essential for the development of new drugs and the modification of existing ones, enhancing their efficacy and selectivity.
Used as a Precursor in the Synthesis of Biologically Active Molecules:
[1,1-Biphenyl]-2,4-diol,3-iodo-(9CI)'s structure and reactivity make it a suitable precursor for the synthesis of biologically active molecules. These molecules can be used in the development of new drugs targeting various diseases and conditions.
Used as a Scaffold in Drug Discovery:
[1,1-Biphenyl]-2,4-diol,3-iodo-(9CI) has the potential to act as a scaffold in drug discovery, providing a foundation for the development of novel therapeutic agents. Its unique structure and properties make it an interesting target for further investigation and study in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 549505-36-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,9,5,0 and 5 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 549505-36:
(8*5)+(7*4)+(6*9)+(5*5)+(4*0)+(3*5)+(2*3)+(1*6)=174
174 % 10 = 4
So 549505-36-4 is a valid CAS Registry Number.
549505-36-4Relevant academic research and scientific papers
Bonnichon, Florent,Grabner, Gottfried,Richard, Claire,Lavedrine, Bernadette
, p. 591 - 596 (2003)
The photolysis of 2-iodophenol (2-IPhOH) was investigated by means of laser flash photolysis and product studies. Two major heterolytic dehalogenation pathways could be evidenced upon irradiation of anionic 2-IPhO-: ring contraction leading to cyclopentadienic acids via a Wolff rearrangement (φa = 0.11 ± 0.02), and α-ketocarbene formation (φc = 0.03 ± 0.01) yielding products characteristic for triplet carbene reactivity. In contrast, the irradiation of neutral 2-IPhOH leads mainly to homolytic cleavage of the carbon-halogen bond (φ = 0.08 ± 0.01) with subsequent formation of biphenyls in deoxygenated solution. This specific reaction, which is not observed with other halogenated phenols, is explained by the low energy of the C-I bond. The relative efficiencies of the heterolytic pathways in the halogenophenol series are discussed in terms of the multiplicity of the excited states involved and of the internal heavy atom effect.
