549514-84-3Relevant academic research and scientific papers
Synthesis, radio-LC-MS analysis and biodistribution in mice of 99mTc-NIM-BAT
Bormans,Cleynhens,De Groot,Mortelmans,Moretti,Verbruggen
, p. 575 - 585 (2007/10/03)
S,S'-bis-trityl-N-BOC-1,2-ethylenedicysteamine (S,S'-bis-trityl-N-BOC-BAT) was conjugated to 2-nitroimidazole (NIM) through a propylene spacer in order to provide a precursor for a potential technetium-99 m labelled hypoxia tracer. For labelling with tech
S-trityl protection of bis-amino bis-thiol (BAT) chelator enables flexible derivatisation and facile labelling with technetium-99m
Cleynhens, Bernard J.,Bormans, Guy M.,Vanbilloen, Hubert P.,Vanderghinste, Dominique V.,Kieffer, Davy M.,De Groot, Tjibbe J.,Verbruggen, Alfons M.
, p. 2597 - 2600 (2007/10/03)
We have coupled S,S′-bis-trityl N-BOC protected 1,2-ethylenedicysteamine, a bis-amino bis-thiol (BAT) tetraligand, via a propylene or ethylene spacer to several biologically active molecules including 2-nitroimidazole, desethylflumazenil, a beta-CIT analo
