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549528-09-8

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549528-09-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 549528-09-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,9,5,2 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 549528-09:
(8*5)+(7*4)+(6*9)+(5*5)+(4*2)+(3*8)+(2*0)+(1*9)=188
188 % 10 = 8
So 549528-09-8 is a valid CAS Registry Number.

549528-09-8Relevant articles and documents

Design, synthesis, and evaluation of β-galactosylceramide mimics promoting β-glucocerebrosidase activity in keratinocytes

Fukunaga, Kyoko,Yoshida, Masahiro,Nakajima, Fumio,Uematsu, Rie,Hara, Mariko,Inoue, Shintaro,Kondo, Hirosato,Nishimura, Shin-Ichiro

, p. 813 - 815 (2007/10/03)

We have established an efficient synthesis of mimics of β-galactosylceramide (β-GalCer) increasing a β-glucocerebrosidase (β-GlcCer'ase) activity that associates with the skin barrier function. Among the synthetic β-GalCer analogues (6a-6e) described herein, compound 6e exhibited a potent effect on the activation of β-GlcCer'ase function in vitro and reduced the transepidermal water loss (TEWL) level in a UVB-induced barrier disrupted mice model. These findings indicated that compound 6e could be useful for cosmetics and medicines to improve skin barrier function.

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