54994-72-8Relevant academic research and scientific papers
(E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction
Wang, Guangcheng,Peng, Zhiyun,Peng, Shanshan,Qiu, Jie,Li, Yongjun,Lan, Yanyu
, p. 3350 - 3355 (2018)
A series of (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides have been synthesized and evaluated for their anticancer activity in human hepatocellular liver carcinoma HepG2 and breast adenocarcinoma MCF-7 cell lines. Among all the test
(DHQ)2AQN-catalyzed asymmetric substitution of isatin-derived hydrazones with O-boc-protected morita-baylis-hillman adducts: A strategy for synthesizing enantioenriched azo compounds incorporating an oxindole scaffold
Yang, Hai-Bin,Zhao, Yun-Zhou,Sang, Rui,Shi, Min
supporting information, p. 3519 - 3528 (2014/05/06)
The first example for the preparation of enantioenriched azo compounds from hydrazones and Morita-Baylis-Hillman adducts has been developed, affording azo compounds incorporating an oxindole scaffold in up to 91% yield along with a 93% ee value under the catalysis of (DHQ)2AQN.
