55-27-6

Basic information

• Product Name: DL-NORADRENALINE HYDROCHLORIDE
• Synonyms: (+/-)-NORADRENALIN HYDROCHLORIDE;[+-]-NORADRENALIN HYDROCHLORIDE;(+/-)-NOREPINEPHRINE HYDROCHLORIDE;[+-]-NOREPINEPHRINE HYDROCHLORIDE;2-AMINO-1-(3,4-DIHYDROXYPHENYL)ETHANOL HYDROCHLORIDE;(+/-)-3,4-DIHYDROXYPHENYLETHANOLAMINE HYDROCHLORIDE;3,4-DIHYDROXYPHENYLETHANOLAMINE HYDROCHLORIDE;(+/-)-1-(3,4-DIHYDROXYPHENYL)-2-AMINOETHANOL HYDROCHLORIDE
• CAS NO: 55-27-6
• Molecular Formula: C₈H₁₂NO₃*Cl
• Molecular Weight: 205.64
• EINECS: 200-229-8
• Product Categories: Standards - 13C & 2H for GC-Mass Spectrometry;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 55-27-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 140-144 °C (dec.)
• Boiling Point: 442.6°Cat760mmHg
• Flash Point: 221.5°C
• Appearance: off-white to tan/crystalline
• Density: 1.397g/cm³
• Vapor Pressure: 1.3E-08mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: water: soluble50mg/mL, clear to slightly hazy, faintly yellow to
• BRN: 3707003
• CAS DataBase Reference: DL-NORADRENALINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: DL-NORADRENALINE HYDROCHLORIDE(55-27-6)
• EPA Substance Registry System: DL-NORADRENALINE HYDROCHLORIDE(55-27-6)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 36/37/39-45
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: DN6650000
• F: 10
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 55-27-6(Hazardous Substances Data)

Usage

Chemical Properties

White to Off-White Solid

Uses

DL-Norepinephrine hydrochloride is suitable adrenergic drug used in the following studies:To investigate the effects of adrenergic drugs on lantern of larval fly.To evaluate the ability of α-adrenergic stimulation in the presence of elevated calcium levels to induce delayed after depolarizations and triggered activity in Purkinje fibers isolated from cat hearts.Simultaneous reduction and surface functionalization of graphene oxide by a one-step poly(norepinephrine) functionalization.

General Description

DL-Norepinephrine hydrochloride is an adrenergic drug.

Safety Profile

Poison by intraperitoneal andsubcutaneous routes. Experimental reproductive effects.When heated to decomposition it emits toxic fumes ofNOx and HCl.

InChI:InChI=1/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1/t8-/m0/s1

Upstream product

• 1207201-66-8 tert-butyl 2-(3,4-dihydroxyphenyl)-2-hydroxyethylcarbamate 
• 5090-29-9 1-(3,4-dihydroxyphenyl)-1-oxo-2-amino-ethan-hydrochlorid 

Downstream Products

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• 88719-36-2 4-[2-(4-Amino-1-methyl-butylamino)-1-hydroxy-ethyl]-benzene-1,2-diol; hydrochloride 
• 88719-35-1 4-[2-(3-Amino-1-methyl-propylamino)-1-hydroxy-ethyl]-benzene-1,2-diol; hydrochloride 
• 88719-49-7 N-{6-[2-(3,4-Dihydroxy-phenyl)-2-hydroxy-ethylamino]-heptyl}-4-methyl-benzamide; hydrochloride 
• 88719-60-2 N-{5-[2-(3,4-Dihydroxy-phenyl)-2-hydroxy-ethylamino]-hexyl}-2-methyl-benzamide; hydrochloride 
• 88719-48-6 N-{5-[2-(3,4-Dihydroxy-phenyl)-2-hydroxy-ethylamino]-hexyl}-4-methyl-benzamide; hydrochloride 
• 95483-99-1 N-{4-[2-(3,4-Dihydroxy-phenyl)-2-hydroxy-ethylamino]-pentyl}-2-methyl-benzamide; hydrochloride 
• 88719-47-5 N-{4-[2-(3,4-Dihydroxy-phenyl)-2-hydroxy-ethylamino]-pentyl}-4-methyl-benzamide; hydrochloride 
• 88719-46-4 N-{3-[2-(3,4-Dihydroxy-phenyl)-2-hydroxy-ethylamino]-butyl}-4-methyl-benzamide; hydrochloride 
• 24159-36-2 dopamine β-sulfonate 
• 95484-08-5 C₂₉H₄₂N₆O₇*ClH 
• 95483-85-5 {6-[2-(3,4-Dihydroxy-phenyl)-2-hydroxy-ethylamino]-heptyl}-carbamic acid benzyl ester; hydrochloride 
• 95483-02-6 (4-Methyl-benzoyl)-carbamic acid 4-[2-(3,4-dihydroxy-phenyl)-2-hydroxy-ethylamino]-pentyl ester 
• 88733-16-8 1-{5-[2-(3,4-Dihydroxy-phenyl)-2-hydroxy-ethylamino]-hexyl}-3-p-tolyl-urea; hydrochloride 

Relevant articles and documents

PROCESS FOR PREPARATION OF (DL) -NOREPINEPHRINE ACID ADDITION SALT, A KEY INTERMEDIATE OF (R) - (-) - NOREPINEPHRINE

The invention discloses a process for preparation of (dl)-norepinephrine salt by reacting 3,4-dihydroxy-a-haloacetophenone with hexamethylenetetramine to provide hexamine salt; followed by hydrolysis and hydrogenation. The invention also discloses a novel intermediate formed in the process and its synthesis.

On the interactions of catecholamines with N-methylnicotinamide cation: A UV spectral study

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