55000-57-2

Basic information

• Product Name: 2-Deoxy-2-fluoro-α-D-arabinopyranose triacetate
• Synonyms: 2-Deoxy-2-fluoro-α-D-arabinopyranose triacetate
• CAS NO: 55000-57-2
• Molecular Formula: C11H15FO7
• Molecular Weight: 278.2310032
• Mol File: 55000-57-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Deoxy-2-fluoro-α-D-arabinopyranose triacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Deoxy-2-fluoro-α-D-arabinopyranose triacetate(55000-57-2)
• EPA Substance Registry System: 2-Deoxy-2-fluoro-α-D-arabinopyranose triacetate(55000-57-2)

Safety Data

• Hazardous Substances Data: 55000-57-2(Hazardous Substances Data)

Upstream product

• 78138-89-3 2-Bromo-2-deoxy-D-arabinono-γ-lactone 
• 97549-81-0 2-deoxy-2-fluoro-α-D-arabinopyranose 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Preparation of 2,3-Epoxyaldonolactones and their Conversion into 2-Fluoro-2-deoxy-aldonolactones and -sugars

Treatment of the 2-bromo-2-deoxylactones 1, 2 and 8 with potassium fluoride in acetonitrile or acetone gives the corresponding 2,3-epoxylactones 4,5 and 10, respectively.The γ-lactones 5 and 10 were in equilibrium with the corresponding δ-lactones 7 and 12.The 2,5-dibromo-2,5-dideoxypentonolactones 3 and 9 gave the 2,3-epoxylactones 6 and 11, respectively, when treated with potassium carbonate in acetone.By treatment of the 2,3-epoxylactones with Et3N*3HF at 70 deg C for 3-13 days the 2-fluoro-2-deoxylactones 13, 15 and 18 were obtained in 57-69 percent yield; 15 and 18 were converted into 2-fluoro-2-deoxy-D-xylose (17) and -D-arabinose (19), respectively.Hydrolysis of 13 gave crystalline 2-fluoro-2-deoxy-L-threonic acid.