55007-22-2

Usage

InChI:InChI=1/C12H14O4/c1-8-3-5-11(16-2)9(7-8)10(13)4-6-12(14)15/h3,5,7H,4,6H2,1-2H3,(H,14,15)/p-1

Upstream product

• 103987-17-3 4-(2-hydroxy-5-methylphenyl)-4-oxobutanoic acid 
• 77-78-1 dimethyl sulfate 
• 108124-66-9 ethyl-4-keto-γ-(2-methoxy-5-methylphenyl)-butyrate 

Downstream Products

• 74285-03-3 5-(2-methoxy-5-methyl-phenyl)-dihydro-furan-2-one 
• 103987-17-3 4-(2-hydroxy-5-methylphenyl)-4-oxobutanoic acid 
• 20483-30-1 4-(2-methoxy-5-methyl-phenyl)-4-oxo-butyric acid methyl ester 
• 58404-64-1 4-(2-methoxy-5-methyl-phenyl)-butyric acid 
• 109560-08-9 5-(2-methoxy-5-methyl-phenyl)-5-(2-methoxy-phenyl)-dihydro-furan-2-one 
• 5732-06-9 1-(2-methoxy-5-methyl-phenyl)-1,4,4-tris-(2-methoxy-phenyl)-buta-1,3-diene 
• 115386-99-7 2-(2-methoxy-5-methyl-phenyl)-2,5,5-tris-(2-methoxy-phenyl)-tetrahydro-furan 
• 106165-92-8 5-(2-methoxy-5-methyl-phenyl)-5-methyl-dihydro-furan-2-one 

Relevant academic research and scientific papers

TETRAHYDRO-6,7-DIMETHOXY-1H-BENZ[E]ISOINODOLINES USEFUL IN THE TREATMENT OF HYPERTENSION AND AS SEDATIVES

Disclosed herein are tetrahydro-benzo e!isoindolines represented by the formula STR1 wherein R, R 1 and R 2 are independently selected from hydrogen, loweralkyl of 1 to 4 carbon atoms, hydroxy, loweralkoxy of 1 to 3 carbon atoms, allyloxy, benzyloxy, benzoyloxy, thiomethyl, halo, STR2 wherein t is 0 or 1, n is 0 to 5 and R 11 and R 14 are independently selected from hydrogen, halo, hydroxy, loweralkyl of 1 to 4 carbon atoms, loweralkoxy of 1 to 3 carbon atoms or amino; orR and R. sub.1, or R 1 and R 2 can be taken together to form a methylenedioxy or ethylenedioxy bridge; with the proviso that at least one of R, R 1 or R 2 must be other than hydrogen and the proviso that two of R, R 1, or R 2 must be other than methoxy in the 7 and 8 positions when the remaining one of R, R 1 or R 2 is hydrogen; andR 3 is hydrogen, loweralkyl of 1 to 4 carbon atoms, halo-substituted loweralkyl of 1 to 4 carbon atoms, amino-substituted loweralkyl of 1 to 4 carbon atoms, amino-substituted arylalkyl, allyl, thioloweralkyl, loweralkanol, or STR3 wherein R 12 and R 13 are independently selected from hydrogen, hydroxy, amino, loweralkoxy of 1 to 3 carbon atoms and s is 1 to 3; or STR4 wherein m is 0, 1 or 2, p is 0 or 1, R 7 is hydrogen or loweralkyl of 1 to 4 carbon atoms and R 8 and R 9 are independently selected from hydrogen, hydroxy, methoxy, loweralkyl of 1 to 4 carbon atoms, or halo, or R 8 and R 9 can be taken together to form a methylenedioxy or ethylenedioxy bridge; or 1,4-benzodioxan of the formula STR5 wherein q is 1, 2 or 3, and R 10 is hydrogen, methoxy, amino, or halo; and the pharmaceutically acceptable salts thereof.

2-Aminomethyl-3,4-dihydronaphthalenes

Compounds of the formula STR1 and pharmaceutically acceptable salts thereof, wherein X and Y are independently H, F, Cl, Br, alkyl having up to four carbons, or alkoxy having up to four carbons, but X and Y are not both H, and Z is a secondary or tertiary amino group, are useful as analgesics and tranquillizing agents for mammals.