55008-25-8Relevant academic research and scientific papers
Khellinone Derivatives as Blockers of the Voltage-Gated Potassium Channel Kv1.3: Synthesis and Immunosuppressive Activity
Baell, Jonathan B.,Gable, Robert W.,Harvey, Andrew J.,Toovey, Nathan,Herzog, Tanja,H?nsel, Wolfram,Wulff, Heike
, p. 2326 - 2336 (2007/10/03)
The voltage-gated potassium channel Kv1.3 constitutes a promising new target for the treatment of T-cell-mediated autoimmune diseases such as multiple sclerosis. In this study, we report the discovery of two new classes of Kv1.3 blockers based on the natu
