5503-75-3 Usage
Uses
Used in Pharmaceutical Industry:
5-[(2-bromophenyl)methylidene]-2-sulfanylidene-thiazolidin-4-one is used as a starting material for the development of antiviral and antibacterial drugs due to its potential to combat various infectious diseases by inhibiting the growth and replication of pathogens.
Used in Enzyme Inhibition:
In the field of biochemistry, 5-[(2-bromophenyl)methylidene]-2-sulfanylidene-thiazolidin-4-one is utilized as an enzyme inhibitor, targeting specific enzymes that play a role in various diseases. Its inhibitory properties can be harnessed to modulate biological processes and treat associated conditions.
Used in Anti-inflammatory Applications:
5-[(2-bromophenyl)methylidene]-2-sulfanylidene-thiazolidin-4-one is employed as an anti-inflammatory agent, leveraging its capacity to reduce inflammation and alleviate symptoms associated with inflammatory conditions. This application can be particularly beneficial in the treatment of chronic inflammatory diseases.
Used in Organic Synthesis:
In the chemical industry, 5-[(2-bromophenyl)methylidene]-2-sulfanylidene-thiazolidin-4-one is used as an intermediate in organic synthesis, contributing to the creation of a wide range of biologically active compounds with diverse applications in medicine and other fields.
Used in Medicinal Chemistry Research:
5-[(2-bromophenyl)methylidene]-2-sulfanylidene-thiazolidin-4-one is utilized in medicinal chemistry research as a key compound for exploring its therapeutic benefits and potential applications in treating various diseases and conditions. Ongoing studies aim to fully understand its mechanisms of action and optimize its use in pharmaceutical formulations.
Check Digit Verification of cas no
The CAS Registry Mumber 5503-75-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,0 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5503-75:
(6*5)+(5*5)+(4*0)+(3*3)+(2*7)+(1*5)=83
83 % 10 = 3
So 5503-75-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H6BrNOS2/c11-7-4-2-1-3-6(7)5-8-9(13)12-10(14)15-8/h1-5H,(H,12,13,14)/b8-5+
5503-75-3Relevant academic research and scientific papers
Molecular modeling of drug-pathophysiological Mtb protein targets: Synthesis of some 2-thioxo-1, 3-thiazolidin-4-one derivatives as anti-tubercular agents
Noorulla,Suresh, Ayyadurai Jerad,Devaraji, Vinod,Mathew, Bijo,Umesh, Devi
, p. 682 - 696 (2017/07/13)
Twenty novel 2-thioxo-1, 3-thiazolidin-4-one derivatives (5a-5t) were synthesized and evaluated for their antitubercular activity. The structure of the compounds was confirmed by IR, NMR and Mass Spectroscopy methods. In addition, single-crystal X-ray diffraction was performed for compound 5a. All the synthesized compounds were screened for their in-vitro antimycobacterial activity against MTB (H37RV, ATCC No: 27294) by Alamar Blue assay method. Compounds 5r, 5k, 5t displayed most potent in-vitro activity with MICs of 0.05, 0.1, 0.2 μg/ml concentrations respectively which are comparatively potent than the standards. Molecular docking and dynamics simulations were performed to find out the plausible mechanism of the titled compounds.
Synthesis and characterization of (Z)-5-arylmethylidenerhodanines with photosynthesis-inhibiting properties
Opletalova, Veronika,Dolezel, Jan,Kralova, Katarina,Pesko, Matus,Kunes, Jiri,Jampilek, Josef
experimental part, p. 5207 - 5227 (2011/08/06)
A series of rhodanine derivatives was prepared. The synthetic approach, analytical and spectroscopic data of all synthesized compounds are presented. Lipophilicity of all the discussed rhodanine derivatives was analyzed using the RP-HPLC method. The compo
