550350-59-9Relevant academic research and scientific papers
Pd0-catalyzed intramolecular α-arylation of sulfones: Domino reactions in the synthesis of functionalized tetrahydroisoquinolines
Solé, Daniel,Pérez-Janer, Ferran,Mancuso, Raffaella
supporting information, p. 4580 - 4584 (2015/03/18)
A new strategy for the synthesis of tetrahydroisoquinolines based on the Pd0-catalyzed intramolecular a-arylation of sulfones is reported. The combination of this Pd-catalyzed reaction with intermolecular Michael and aza-Michael reactions allows the development of two- and three-step domino processes to synthesize diversely functionalized scaffolds from readily available starting materials.
Synthesis of substituted aziridines via intramolecular reactions of β-N-chloroethylamino carbanions
Makosza, Mieczyslaw,Bobryk, Karolina,Krajewski, Dariusz
experimental part, p. 1511 - 1524 (2009/07/17)
Simple and efficient method of synthesis of 2-alkoxycarbonyl, 2-cyano, 2-phenylsulfonyl N-alkylaziridines was elaborated via intramolecular nucleophiles substitution of chloride in 1-N-chloro-2-alkoxycarbonyl (cyano, phenylsulfonyl) ethyl amines. These su
Enantioselective phase-transfer-catalyzed intramolecular Aza-Michael reaction: Effective route to pyrazino-indole compounds
Bandini, Marco,Eichholzer, Astrid,Tragni, Michele,Umani-Ronchi, Achille
, p. 3238 - 3241 (2008/12/23)
(Chemical Equation Presented) Producing polycycles: A mild and direct stereocontrolled route to pharmacologically active pyrazino-indol-1-ones has been developed. The optimal phase-transfer conditions provide variously functionalized ring-closed compounds
