55037-81-5

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-METHOXYBENZYL) PIPERAZINE is used as a building block for the synthesis of various pharmaceuticals and drug candidates due to its potential biological activities and its role in the development of new therapeutic agents.
Used in Medicinal Chemistry Research:
1-(2-METHOXYBENZYL) PIPERAZINE is used as a research compound for investigating its potential antipsychotic and antidepressant effects, as well as its interaction with the serotonin 5-HT1A receptor, which plays a crucial role in mood and anxiety regulation.
Used in Drug Discovery:
1-(2-METHOXYBENZYL) PIPERAZINE is utilized in drug discovery processes to explore its therapeutic properties and to develop new drugs targeting mental health disorders based on its affinity for specific receptors and biological pathways.

Downstream Products

• 1277167-57-3 C₂₂H₂₃ClN₄O₂ 
• 1448676-85-4 2-cyclopropyl-6,7-dimethoxy-4-(4-(2-methoxybenzyl)piperazin-1-yl)quinazoline 

Relevant academic research and scientific papers

LMO2 PROTEIN INHIBITORS

The present invention relates to compounds of Formula (I) that function as LMO2 activity: Formula (I) wherein R1, X1, X2, X3, Q, R2, R3 and R4 are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which LMO2 activity is implicated.

Discovery of 3-aryl-5-acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor

A series of 3-aryl-5-acylpiperazinyl-pyrazoles (e.g., 3a-b) initially identified through a high-throughput screening campaign using the aequorin Ca2+ bioluminescence assay as novel, potent small molecule antagonists of the G protein-coupled hum

Benzopyrone derivatives exhibiting anti-allergic activity

Benzopyrones of the formula STR1 wherein R1 is a hydrogen or halogen atom or a hydroxyl, lower alkyl, alkoxy, alkylthio or trifluoromethyl radical, R2, r3, r4 and R5 each independently is hydrogen, a halogen atom, a hydroxyl radical, a lower alkyl or lower alkoxy radical, or a lower alkyl or lower alkoxy radical substituted by at least one of hydroxyl, halogen, mesyloxy or tosyloxy or by an oxirane, dioxane or dioxolane ring, A is a lower alkylene radical, and n is 0, 1 or 2, And salts thereof exhibit anti-allergic activity.