Cas 550378-02-4,1-Piperidinesulfonyl chloride, 4-[3-(2,3-dichlorophenyl)-1-methyl-1H-pyrazol-5-yl]-

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Check Digit Verification of cas no

The CAS Registry Mumber 550378-02-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,0,3,7 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 550378-02:
(8*5)+(7*5)+(6*0)+(5*3)+(4*7)+(3*8)+(2*0)+(1*2)=144
144 % 10 = 4
So 550378-02-4 is a valid CAS Registry Number.

550378-02-4Upstream product

550378-02-4Downstream Products

550378-03-5 (3-{4-[5-(2,3-dichloro-phenyl)-2-methyl-2H-pyrazol-3-yl]-piperidine-1-sulfonylamino}-propyl)-carbamic acid tert-butyl ester

550378-02-4Relevant academic research and scientific papers

Identification of nonpeptidic small-molecule inhibitors of interleukin-2

Waal, Nathan D.,Yang, Wenjin,Oslob, Johan D.,Arkin, Michelle R.,Hyde, Jennifer,Lu, Wanli,McDowell, Robert S.,Yu, Chul H.,Raimundo, Brian C.

, p. 983 - 987 (2007/10/03)

The identification, design, and synthesis of a series of novel sulfamide- and urea-based small-molecule antagonists of the protein-protein interaction IL-2/IL-2Rα are described. Installation of a furan carboxylic acid fragment onto a low-micromolar sulfamide resulted in a 23-fold improvement in activity, providing a sub-micromolar, nonpeptidic IL-2 inhibitor (IC 50 = 0.60 μM).

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