55107-38-5Relevant academic research and scientific papers
Synthesis of enantiopure benzyl homoallylamines by indium-mediated barbier-type allylation combined with enzymatic kinetic resolution: Towards the chemoenzymatic synthesis of N-containing heterocycles
Hietanen, Ari,Saloranta, Tuna,Rosenberg, Sara,Laitinen, Evelina,Leino, Reko,Kanerva, Liisa T.
experimental part, p. 909 - 919 (2010/04/23)
Barbier-type indium-mediated allylations of different N, N(dimethylsulfamoyl)-protected aldimines with a number of allyl bromides followed by high-yielding deprotection afforded allylic amines in good to excellent yields, The racemic amines were then subj
Carbon-carbon bond formations at the benzylic positions of N-benzylxanthone imines and N-benzyldi-1-naphthyl ketone imine
Niwa, Takashi,Suehiro, Takafumi,Yorimitsu, Hideki,Oshima, Koichiro
experimental part, p. 5125 - 5131 (2009/11/30)
Two N-benzyl imines are designed to allow for carbon-carbon bond formations at the aminated benzylic positions. Direct benzylic arylation reactions of N-benzylxanthone imine with aryl chlorides proceed under palladium catalysis in the presence of cesium hydroxide, yielding the corresponding benzhydrylamine derivatives. Alkylation reactions of N-benzyldi-1-naphthyl ketone imine with alkyl halides in the presence of potassium tert-butoxide afford the corresponding 1-phenylalkylamines in high yields. Conjugate addition of N-benzyldi-1-naphthyl ketone imine is also described.
Organometallic reactions in aqueous media. Indium-mediated allylation of sulfonimines
Chan, Tak Hang,Lu, Wenshuo
, p. 8605 - 8608 (2007/10/03)
Barbier-type allylation of sulfonimines with indium and allyl bromide to give homoallylic sulfonamides can be performed smoothly in organic solvents and in aqueous media. The regio- and the stereoselectivity of the reaction have been examined.
