55136-52-2

Basic information

• Product Name: pent-2-ynal
• Synonyms: 2-Pentynal; Pent-2-ynal
• CAS NO: 55136-52-2
• Molecular Formula: C₅H₆O
• Molecular Weight: 82.1005
• Mol File: 55136-52-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 129.3°C at 760 mmHg
• Flash Point: 38.9°C
• Density: 0.895g/cm³
• Vapor Pressure: 10.2mmHg at 25°C
• Refractive Index: 1.424
• CAS DataBase Reference: pent-2-ynal(CAS DataBase Reference)
• NIST Chemistry Reference: pent-2-ynal(55136-52-2)
• EPA Substance Registry System: pent-2-ynal(55136-52-2)

Safety Data

• Hazardous Substances Data: 55136-52-2(Hazardous Substances Data)

Upstream product

• 6261-22-9 pent-2-yn-1-ol 
• 18229-77-1 2-pentynal-diethyl-acetal 
• 117785-62-3 1-trimethylsilyloxy-2-pentyne 

Downstream Products

• 13808-71-4 3-ethyl-1H-pyrazole 
• 6261-22-9 pent-2-yn-1-ol 
• 54664-97-0 (9Z,11Z)-9,11-tetradecadienol acetate 
• 358750-31-9 (2S,4S)-2-((2S,3S)-3-Ethyl-oxiranyl)-4-phenyl-oxazolidine-3-carboxylic acid phenylamide 
• 358750-21-7 (2S-cis)-2-(1-butynyl)-4,N-diphenyl-3-oxazolidinecarboxamide 
• 358750-22-8 {2S-[cis-(Z)]}-2-(1-butenyl)-4,N-diphenyl-3-oxazolidinecarboxamide 
• 50767-79-8 (9Z,11E)-9,11-tetradecadiene-1-yl acetate 
• 30562-09-5 (9E,11Z)-tetradeca-9,11-dien-1-yl acetate 
• 54664-98-1 (E,E)-9,11-tetradecadienyl acetate 

Relevant articles and documents

Gas-liquid segmented flow microfluidics for screening copper/tempo-catalyzed aerobic oxidation of primary alcohols

Aerobic oxidation using a combination of copper salts and 2,2,6,6-tetramethylpiperidine N-oxyl (TEMPO) represent useful tools for organic synthesis and several closely related catalyst systems have been reported. To gain further insights, these catalytic systems were evaluated in a gas-liquid segmented flow device. The improvement of oxygen mass transfer has a significant influence on the turnover-limiting step. Hence, an improved catalytic system using copper(II) as copper source was implemented in a microreactor for the safe and efficient oxidation of primary alcohol.

The conjugate addition-Peterson olefination reaction for the preparation of cross-conjugated cyclopentenone, PPAR-γ ligands

5-Alkylidenecyclopent-2-enones 15a-q may be prepared via a conjugate addition-Peterson olefination sequence, best achieved in one-pot, using exo-2-trimethylsilyl-3a,4,7,7a-tetrahydro-4,7-methanoinden-1-one 12, followed by a retro-Diels-Alder reaction. The geometry of the exocyclic alkene may be controlled according to the use of organometallic species in the conjugate addition step; organocuprate reagents are found to selectively lead to the formation of E-exocyclic alkene adducts, whereas Grignard reagents favour the formation of Z-alkenyl isomers. The use of enantiomerically enriched 12, accessed from an asymmetric Pauson-Khand reaction, affords the corresponding enantioenriched 5-alkylidenecyclopent-2-enones and this approach is exemplified by the short, stereoselective total syntheses of two cyclopentenone phytoprostanes 51 and 13,14-dehydrophytoprostane J165. The ability of this family of synthetic compounds to activate the peroxisome proliferator activated receptor-γ is reported.

A new method for oxidation of various alcohols to the corresponding carbonyl compounds by using n-t-butylbenzenesulfinimidoyl chloride

Various primary and secondary alcohols were smoothly oxidized to the corresponding aldehydes and ketones by using a new oxidizing agent, N-t-butylbenzenesulfinimidoyl chloride (4a), in the coexistence of DBU or zinc oxide. The present oxidation proceeded under mild conditions via five-membered intramolecular proton-transfer of an alkyl arenesulfinimidate intermediate.