55149-83-2

Basic information

• Product Name: Ethyl 2-ethoxy-2-iminoacetate hydrochloride
• Synonyms: Ethyl 2-ethoxy-2-iminoacetate hydrochloride;ETHYL 2-ETHOXY-2-IMINOACETATE HCL
• CAS NO: 55149-83-2
• Molecular Formula: C₆H₁₁NO₃*ClH
• Molecular Weight: 181.61738
• Mol File: 55149-83-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 104 °C
• Boiling Point: 196.2 °C at 760 mmHg
• Flash Point: 72.5 °C
• Appearance: /
• Vapor Pressure: 0.34mmHg at 25°C
• CAS DataBase Reference: Ethyl 2-ethoxy-2-iminoacetate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-ethoxy-2-iminoacetate hydrochloride(55149-83-2)
• EPA Substance Registry System: Ethyl 2-ethoxy-2-iminoacetate hydrochloride(55149-83-2)

Safety Data

• Hazardous Substances Data: 55149-83-2(Hazardous Substances Data)

Usage

General Description

Ethyl 2-ethoxy-2-iminoacetate hydrochloride is a chemical compound with the molecular formula C6H12ClNO3. It is a hydrochloride salt form of ethyl 2-ethoxy-2-iminoacetate, which is an ester derivative of glycine. Ethyl 2-ethoxy-2-iminoacetate hydrochloride can be used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It is often utilized in the production of drugs for the treatment of neurological and psychiatric disorders. Additionally, it can also be used as a reagent in organic chemistry reactions. Ethyl 2-ethoxy-2-iminoacetate hydrochloride is a white to off-white crystalline solid with a melting point range of 156-160°C and should be handled and stored according to standard laboratory procedures for chemicals.

InChI:InChI=1/C6H11NO3.ClH/c1-3-9-5(7)6(8)10-4-2;/h7H,3-4H2,1-2H3;1H

Upstream product

• 623-49-4 ethyl cyanoformate 
• 64-17-5 ethanol 

Downstream Products

• 86724-12-1 1-(4-Methoxy-benzyl)-1H-imidazole-2,4-dicarboxylic acid diethyl ester 
• 83566-33-0 ethyl 4-aminoquinazoline-2-carboxylate 
• 69982-16-7 ethyl β-formyloxalamidrazone 

Relevant articles and documents

Pyrrole imidazole ring derivative and medical use thereof wherein the compound represented by the general formula (I) has excellent inhibitory effect on and selectivity of dipeptidyl peptidase IV(DPP-IV)

The present invention relates to a pyrrole imidazole ring derivative and medical use thereof, more particularly a pyrrole imidazole ring derivative represented by the general formula (I) or stereoisomers thereof, pharmaceutically acceptable salts thereof, prodrugs, pharmaceutical compositions containing the derivative, and pharmaceutical applications for the preparation of dipeptidyl peptidase IV(DPP-IV) inhibitors, wherein the definitions of all substitution groups in general formula (I) are the same as those defined in the specification.

Chemoenzymatic method of 1,2,4-triazole nucleoside synthesis: Possibilities and limitations

Possibilities and limitations of chemoenzymatic synthesis of novel structural analogues of an antiviral preparation of Ribavirin (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) were established. A synthesis of various amides of 1H-1,2,4-triazole-3-carboxylic acid and its 5-substituted analogues - potential substrates of purine nucleoside phosphorylase - has been described. Comparative efficiency of preparation methods of these amides, as well as the methods of introduction of functional groups to the C5 position of heterocyclic system, were investigated. Novel analogues of Ribavirin containing various substitutes in the carboxamide group were synthesized. A biotechnological method was developed for the preparation of 1-β-D-ribofuranozyl-1,2,4-triazole-3-carbonitryl, an intermediate in the synthesis of Viramidine, the modern analogue of Ribavirin.

A practical synthesis of ethyl 1,2,4-triazole-3-carboxylate and its use in the formation of chiral 1',2'-seco-nucleosides of ribavirin

A practical and efficient synthesis of ethyl 1,2,4-triazole-3-carboxylate (6a, R'' = H) from ethyl carboethoxyformimidate hydrochloride is described. Alkylation of this heterocycle with the chloromethyl ethers of 1,3-O-dibenzylbutane-1,2R,3S-triol and 1,3