55157-48-7Relevant academic research and scientific papers
Primulin derivative as well as synthesis method and application of primulin derivative
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, (2018/01/11)
The invention discloses a primulin derivative with antibacterial activity shown as the structural general formula (I), wherein R is selected from C2-C20 alkyls. The primulin derivative is prepared from raw materials including m-dihydroxybenzene and a fatty acid derivative by the steps: carrying out Friedel-Crafts acylation and methylation to synthesize a paeonol derivative, and carrying out oxidization after carrying out carbonyl reduction. The primulin derivative has good antibacterial activity and can be used as a potential antibacterial agent.
Synthesis and highly potent hypolipidemic activity of alpha-asarone- and fibrate-based 2-acyl and 2-alkyl phenols as HMG-CoA reductase inhibitors
Mendieta, Aarn,Jimnez, Fabiola,Garduo-Siciliano, Leticia,Mojica-Villegas, Anglica,Rosales-Acosta, Blanca,Villa-Tanaca, Lourdes,Chamorro-Cevallos, Germn,Medina-Franco, Jos L.,Meurice, Nathalie,Gutirrez, Rsuini U.,Montiel, Luisa E.,Cruz, Mara Del Carmen,Tamariz, Joaqun
, p. 5871 - 5882 (2015/01/08)
In the search for new potential hypolipidemic agents, the present study focused on the synthesis of 2-acyl phenols (6a-c and 7a-c) and their saturated side-chain alkyl phenols (4a-c and 5a-c), and on the evaluation of their hypolipidemic activity using a
