55169-04-5Relevant articles and documents
Synthesis, crystal structure, and absolute configuration of the enantiomers of chiral drug xibenolol hydrochloride
Bredikhin, Alexander A.,Bredikhina, Zemfira A.,Kurenkov, Alexey V.,Gubaidullin, Aidar T.
, p. 1359 - 1366 (2017)
Based on the features of its crystallization, racemic 3-(2,3-dimethylphenoxy)propane-1,2-diol 2, the synthetic precursor of the chiral drug xibenolol 1, was resolved into pure enantiomers by the direct method of entrainment. The enantiomers of diol 2 thro
Spontaneous Resolution of Chiral 3-(2,3-Dimethylphenoxy)propane-1,2-diol under the Circumstances of an Unusual Diversity of Racemic Crystalline Modifications
Bredikhin, Alexander A.,Zakharychev, Dmitry V.,Bredikhina, Zemfira A.,Kurenkov, Alexey V.,Krivolapov, Dmitry B.,Gubaidullin, Aidar T.
, p. 4196 - 4206 (2017)
Depending on the conditions of crystallization from solutions, racemic 3-(2,3-dimethylphenoxy)propane-1,2-diol 1 forms three relatively stable crystalline modifications. Each of the crystalline forms, namely, two polymorphic racemic compounds and a racemi