5518-09-2Relevant articles and documents
Preparation of O-Protected Cyanohydrins by Aerobic Oxidation of α-Substituted Malononitriles in the Presence of Diarylphosphine Oxides
Zhang, Dapeng,Lian, Mingming,Liu, Jia,Tang, Shukun,Liu, Guangzhi,Ma, Cunfei,Meng, Qingwei,Peng, Haisheng,Zhu, Daling
, p. 2597 - 2601 (2019/04/17)
A mild, reagent-cyanide-free, and efficient synthesis of O-phosphinoyl-protected cyanohydrins from readily available α-substituted malononitriles was realized using diarylphosphine oxides in the presence of O2. Mechanistic studies indicated that in addition to the initial aerobic oxidation of the malononitrile derivative notable features of this process include the formation of a tetrahedral intermediate and a subsequent intramolecular rearrangement. The phosphinoyl-protecting group can be removed by alcoholysis or by reduction with DIBAL-H.
A highly efficient catalytic system for cross-coupling of aryl chlorides and bromides with malononitrile anion by palladium carbene complexes
Gao, Chengwei,Tao, Xiaochun,Qian, Yanlong,Huang, Jiling
, p. 1444 - 1445 (2007/10/03)
Six imidazolium chlorides (1-6) as precursors of 1,3-diaryl substituted N-heterocyclic carbene ligands were synthesized and evaluated in palladium-catalyzed cross-coupling reactions of aryl chlorides and bromides with malononitrile in the presence of NaH.
Chromophoric compounds and process for their preparation
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, (2008/06/13)
The invention relates to chromophoric NLO-active compounds of the general formula and to a process for preparing such compounds. The compounds according to the invention can be used for preparing NLO-active polymers and thus for constructing electrooptica
A New Method of Synthesis of Arylmalononitriles catalysed by a Palladium Complex
Uno, Mitsunari,Seto, Koji,Takahashi, Shigetoshi
, p. 932 - 933 (2007/10/02)
Arylmalononitriles are prepared in good yields using a palladium-catalysed coupling reaction between aryl halides and malononitrile.