5518-91-2

Basic information

• Product Name: 5-hydroxy-2,7-dimethoxynaphthalene-1,4-dione
• Synonyms: NAPHTHOQUINONE, 2,7-DIMETHOXY-5-HYDROXY
• CAS NO: 5518-91-2
• Molecular Formula: C₁₂H₁₀O₅
• Molecular Weight: 234.2048
• Mol File: 5518-91-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 499.3°C at 760 mmHg
• Flash Point: 200.3°C
• Density: 1.41g/cm³
• Vapor Pressure: 1.36E-10mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: 5-hydroxy-2,7-dimethoxynaphthalene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-2,7-dimethoxynaphthalene-1,4-dione(5518-91-2)
• EPA Substance Registry System: 5-hydroxy-2,7-dimethoxynaphthalene-1,4-dione(5518-91-2)

Safety Data

• Hazardous Substances Data: 5518-91-2(Hazardous Substances Data)

Upstream product

• 24605-23-0 2-chloro-5-methoxybenzoquinone 
• 90857-62-8 ((E)-1,3-Dimethoxy-buta-1,3-dienyloxy)-trimethyl-silane 
• 186581-53-3 diazomethane 
• 479-05-0 flaviolin 
• 13586-04-4 3,6,8-trimethoxy-1-naphthol 

Downstream Products

• 5803-58-7 3,6,8-trimethoxy-1,4-naphthoquinone 
• 2808-46-0 2,7-Dimethoxy-naphthazarin 
• 479-05-0 flaviolin 
• 91776-47-5 fibrostatin C 

Relevant articles and documents

A New Method for Thiomethylation of Hydroxy-1,4-naphthoquinones with N -Acetyl- l -cysteine; First Synthesis of Fibrostatins B, C, and D

A series of N-acetyl-S-[(3-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methyl]-l-cysteine conjugates were obtained in good yields by acid-catalyzed condensation of substituted 2-hydroxy-1,4-naphthoquinones with N-acetyl-l-cysteine and paraformaldehyde. Based on this reaction, a first synthesis of fibrostatins B, C, and D was developed.