55186-89-5

Basic information

• Product Name: 1-Benzyl-1,4-diazepan-5-one
• Synonyms: 1-Benzyl-2,3,6,7-tetrahydro-(1H)-1,4-diazepin-5(4H)-one;1-Benzyl-1,4-diazepan-5-one;1-(phenylmethyl)-1,4-diazepan-5-one;1-Benzyl-1,4-diazepin-5-one;1-Benzyl-5-oxo-1,4-diazepane;NSC45105
• CAS NO: 55186-89-5
• Molecular Formula: C₁₂H₁₆N₂O
• Molecular Weight: 204.27
• Product Categories: Ring Systems;pharmacetical
• Mol File: 55186-89-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 115-117°
• Boiling Point: 379.817°C at 760 mmHg
• Flash Point: 183.507°C
• Appearance: /
• Density: 1.098g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.55
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 16.00±0.20(Predicted)
• CAS DataBase Reference: 1-Benzyl-1,4-diazepan-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-1,4-diazepan-5-one(55186-89-5)
• EPA Substance Registry System: 1-Benzyl-1,4-diazepan-5-one(55186-89-5)

Safety Data

• Hazardous Substances Data: 55186-89-5(Hazardous Substances Data)

Usage

Uses

1-Benzyl-1,4-diazepan-5-one is a diazepane intermediate that can be used as an inhibitor of human nitric oxide synthesis.

InChI:InChI=1/C12H16N2O/c15-12-6-8-14(9-7-13-12)10-11-4-2-1-3-5-11/h1-5H,6-10H2,(H,13,15)

Upstream product

• 949-69-9 N-benzyl-4-(N-hydroxyimino)piperidine 
• 3612-20-2 1-phenylmethyl-4-piperidone 

Downstream Products

• 214911-30-5 (4-benzyl-7-oxo-[1,4]diazepan-1-yl)-acetic acid ethyl ester 
• 477740-02-6 1-Benzyl-4-(4-bromo-phenyl)-[1,4]diazepan-5-one 
• 214911-34-9 C₃₀H₃₇N₇O₇S₃ 
• 214911-32-7 ethyl 2-(4-benzylsulfonyl-7-oxo-1,4-diazepan-1-yl)acetate 
• 214911-33-8 (7-oxo-4-phenylmethanesulfonyl-[1,4]diazepan-1-yl)-acetic acid 
• 190900-21-1 5-oxo-[1,4]diazepane-1-carboxylic acid tert-butyl ester 
• 34376-54-0 [1,4]diazepan-5-one 
• 4410-12-2 1-benzyl-[1,4]diazepane 

Relevant articles and documents

NOVEL TRIAZINE COMPOUNDS

The present invention relates to novel triazine compounds of formula (1). The present invention also discloses compounds of formula I along with other pharmaceutical ac-ceptable excipients and use of the compounds to modulate the PI3K/ mTOR pathway

PYRAZOLE DERIVATIVE

Not available

New synthesis of (±)-2-piperazinecarboxylic acid

(±)-2-Piperazinecarboxylic acid is prepared from N-carbethoxy-4-piperidone by α Schmidt rearrangement followed by bromation of the lactam; then α Favorskii rearrangement on the monobromolactam intermediate afforded the desired product.