551950-41-5 Usage
General Description
3-(2-chloro-pyridin-4-yl)-acrylic acid ethyl ester is a chemical compound that contains a 3-(2-chloro-pyridin-4-yl) group attached to an acrylic acid ethyl ester. It is commonly used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. 3-(2-CHLORO-PYRIDIN-4-YL)-ACRYLIC ACID ETHYL ESTER has potential uses in the development of new medications for a range of medical conditions. It is important to handle this chemical with care, as it may have harmful effects if not properly managed. Overall, 3-(2-chloro-pyridin-4-yl)-acrylic acid ethyl ester is a significant chemical with potential applications in pharmaceutical research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 551950-41-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,1,9,5 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 551950-41:
(8*5)+(7*5)+(6*1)+(5*9)+(4*5)+(3*0)+(2*4)+(1*1)=155
155 % 10 = 5
So 551950-41-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H10ClNO2/c1-2-14-10(13)4-3-8-5-6-12-9(11)7-8/h3-7H,2H2,1H3/b4-3+
551950-41-5Relevant articles and documents
Dimethyl sulfoxide mediated elimination reactions in 3-aryl 2,3-dihalopropanoates: Scope and mechanistic insights
Li, Wei,Li, Jianchang,Lin, Melissa,Wacharasindhu, Sumrit,Tabei, Keiko,Mansour, Tarek S.
, p. 6016 - 6021 (2008/02/10)
(Chemical Equation Presented) Dimethyl sulfoxide (DMSO) efficiently causes the reductive elimination of 3-aryl 2,3-dibromopropanoates to cinnamates with good yield. With 3-phenyl 2,3-dihalopropanoates, debromination is the major pathway providing 3-phenylacrylate derivatives in high yields, whereas dehydrobromination is a competing pathway with thiophene derivatives. 1H NMR, 81Br NMR, and MS techniques indicated the formation of brominated-DMSO, MeBr, and HBr as byproducts in this transformation with no evidence for the formation of Br2. The dual role of DMSO as a nucleophile and bromine scavenger accounts for the products formed in this reaction.
