55199-24-1

Basic information

• Product Name: 6,7-DIMETHYLINDOLE
• Synonyms: 6,7-DIMETHYLINDOLE;1H-Indole, 6,7-diMethyl-
• CAS NO: 55199-24-1
• Molecular Formula: C₁₀H₁₁N
• Molecular Weight: 145.20104
• Mol File: 55199-24-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 70 °C
• Boiling Point: 276.0±9.0 °C(Predicted)
• Appearance: /
• Density: 1.080±0.06 g/cm3(Predicted)
• PKA: 17.66±0.30(Predicted)
• CAS DataBase Reference: 6,7-DIMETHYLINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-DIMETHYLINDOLE(55199-24-1)
• EPA Substance Registry System: 6,7-DIMETHYLINDOLE(55199-24-1)

Safety Data

• Hazardous Substances Data: 55199-24-1(Hazardous Substances Data)

Usage

General Description

6,7-Dimethylindole is a chemical compound with the molecular formula C10H11N. It is a substituted indole derivative, which is a heterocyclic compound commonly found in plants and some pharmaceuticals. 6,7-Dimethylindole is a pale yellow to brown liquid with a strong, sweet, and flowery odor. This chemical is primarily used as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. It is also used as an indicator in chemical analysis and as a reagent in organic synthesis. Additionally, 6,7-Dimethylindole has been studied for its potential biological and pharmacological activities, including its potential as an antitumor agent and its ability to inhibit the growth of cancer cells. Overall, 6,7-Dimethylindole is a versatile and important chemical with a wide range of applications in various industries.

Upstream product

• 443-86-7 3-fluoro-2-methylaniline 
• 107-21-1 ethylene glycol 
• 87-59-2 2,3-Dimethylaniline 

Downstream Products

• 480435-98-1 3-(6,7-dimethyl-1H-indol-3-yl)-2,5-dichloro[1,4]benzoquinone 

Relevant articles and documents

β-Amino alcohols from anilines and ethylene glycol through heterogeneous Borrowing Hydrogen reaction

Borrowing Hydrogen (BH), also called Hydrogen Autotransfer (HA), reaction with neat ethylene glycol represents a key step in the preparation of β-amino alcohols. However, due to the stability of ethylene glycol, mono-activation has rarely been achieved. Herein, a combination of Pd/C and ZnO is reported as heterogeneous catalyst for this BH/HA reaction. This system results in an extremely air and moisture stable, and economic catalyst able to mono-functionalize ethylene glycol in water, without further activation of the diol. In this work, different diols and aromatic amines have been explored affording a new approach towards amino alcohols. This study reveals how the combination of two solid species can afford interesting catalytic properties in heterogeneous phase. ZnO activates ethylene glycol while Pd/C is the responsible of the BH/HA cycle. This catalytic system has also been found useful to dehydrogenate indoles affording indolines that undergo in situ BH/HA cycle prior to re-aromatization, representing a tandem heterogeneous process.