55221-03-9

Upstream product

• 32174-46-2 methyl (R)-(-)-2-methoxy-2-phenylacetate 
• 611-71-2 (R)-Mandelic Acid 
• 17628-72-7 R-(-)-2-methoxy-2-phenyl ethanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 92502-91-5 Sodium; (Z)-2-methyl-3-oxo-pent-1-en-1-olate 

Downstream Products

• 114114-91-9 ((R)-2-Cyclopenta-2,4-dienyl-1-methoxy-ethyl)-benzene 
• 55163-76-3 (R)-2-methoxy-2-phenylethylamine 
• 55163-70-7 (-)(R)-N-(2-Methoxy-2-phenylethyl)-N-nitrosoharnstoff 
• 55163-72-9 (RS)-(2-ethoxy-2-methoxy-ethyl)-benzene 
• 74345-43-0 (R)-(-)-(2-Phenyl-2-methoxyethan-1-yl)diphenylphosphine 

Relevant academic research and scientific papers

(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist

The pivotal role of the stereocenter at the N-substituent of the 6,7-benzomorphan scaffold was investigated combining synthetic and pharmacological approaches. 2R- and 2S-diastereoisomers of the multitarget MOR/DOR antinociceptive ligand LP2 (1) were synt

The diastereoselective formation of tetraalkoxy[4]resorcinarenes derived from (-)-(2R)-2-methoxy-2-phenylethanol and proof of absolute configurations

The preparation of optically pure (-)-3-[(2R)-2-methoxy-2-phenylethoxy] phenol from resorcinol monobenzoate and its conversion into diastereoisomeric tetraalkoxyresorcin[4]arenes together with proof of the absolute configurations of the products is reported. The results of the study indicate that diastereoselective ring closure of linear tetrameric intermediates is controlled by the steric demand of the alkyl group in the precursor 3-alkoxyphenol.

MUSCARINIC AGONISTS

The present invention relates to compounds of Formula (I): which are agonists of the M-1 muscarinic receptor.

SYNTHESIS OF CHIRAL β-ALKOXY-α,β-UNSATURATED KETONES

The title compounds are synthesized in one-pot from the easily available sodium salts of unsymmetrical 1,3-dicarbonyl derivatives and chiral alkoxides.