55224-99-2Relevant academic research and scientific papers
Enantioselective hydrogenation of (Z)- and (E)-β-arylenamides catalyzed by rhodium complexes of monodentate chiral spiro phosphorous ligands: A new access to chiral β-arylisopropylamines
Zhu, Shou-Fei,Liu, Tao,Yang, Shuang,Song, Song,Zhou, Qi-Lin
supporting information; experimental part, p. 7685 - 7690 (2012/09/07)
A highly enantioselective rhodium-catalyzed hydrogenation of both (Z)- and (E)-β-arylenamides was developed by using monodentate chiral spiro phosphite and phosphine ligands, respectively. The hydrogenation reaction provides an efficient access to optically active β-arylisopropylamines, important building blocks for the synthesis of biologically active compounds.
