552292-52-1Relevant academic research and scientific papers
And as the antagonist aminopyrrolidine deriv. NK1 aminopiperidine (by machine translation)
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Paragraph 0308-0310, (2016/10/08)
A NK 1 antagonist having the formula (I), wherein Ar 1 and Ar 2 are optionally substituted phenyl or heteroaryl, X 1 is an ether, thio or imino linkage, R 4 and R 5 are not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed.
