552311-69-0Relevant academic research and scientific papers
Efficient intramolecular energy transfer between two fluorophores in a bis-branched [3]rotaxane
Yao, Jian,Li, Hong,Xu, Ya-Nan,Wang, Qiao-Chun,Qu, Da-Hui
, p. 3482 - 3490 (2014)
A bis-branched [3]rotaxane, with two [2]rotaxane arms separated by an oligo(para-phenylenevinylene) (OPV) fluorophore, was designed and investigated. Each [2]rotaxane arm employed a difluoroboradiaza-s-indacene (BODIPY) dye-functionalized dibenzo[ 24]crow
Kojic acid–natural product conjugates as mushroom tyrosinase inhibitors
Ashooriha, Morteza,Emami, Saeed,Kardan, Mostafa,Khoshneviszadeh, Mahsima,Khoshneviszadeh, Mehdi,Rafiei, Alireza,Yazdian-Robati, Rezvan
, (2020/07/10)
As part of our effort to develop potential tyrosinase inhibitors, we have conjugated the well-known tyrosinase inhibitor kojic acid (KA) with several phenolic natural products such as umbelliferone, sesamol, thymol, carvacrol, eugenol, isoeugenol, vanilli
Design, synthesis, and SAR analysis of cytotoxic sinapyl alcohol derivatives
Zou, Hong Bin,Dong, Sheng Yi,Zhou, Chang Xin,Hu, Li Hong,Wu, Yi Hang,Li, Hai Bo,Gong, Jing Xu,Sun, Lian Li,Wu, Xiu Mei,Bai, Hua,Fan, Bo Tao,Hao, Xiao Jiang,Stoeckigt, Joachim,Zhao, Yu
, p. 2060 - 2071 (2007/10/03)
Five series totalling 51 of sinapyl alcohol derivatives were designed and synthesized. Their cytotoxicity analyses were performed on six human tumor cell lines such as PC-3, CNE, KB, A549, BEL-7404, and HeLa. Certain sinapyl alcohol derivatives showed significant cytotoxic activities. Compound 14d exhibited especially potent cytotoxicity against the BEL-7404 cell line with an IC 50 value of 0.7 μM, which showed more cytotoxic activity than the positive control, cisplatin. The structure-cytotoxicity relationships were discussed and the CoMFA analysis was performed using the cytotoxic data against HeLa cells as a template.
Click linker: Efficient and high-yielding synthesis of a new family of SPOS resins by 1,3-dipolar cycloaddition
Loeber, Stefan,Rodriguez-Loaiza, Pilar,Gmeiner, Peter
, p. 1753 - 1755 (2007/10/03)
(Matrix presented) Highly efficient methodology for the construction of functionalized resins was presented involving 1,3-dipolar cycloaddition as the key reaction step. On the basis of this concept, the first series of click backbone amide linkers were s
