55233-09-5 Usage
Type of compound
Nitrile compound
Structural components
Contains a phenyl group and a 3-chloro-4-nitrophenyl group attached to a 2-phenylpropane backbone
Usage
Building block for the preparation of various pharmaceutical products and agrochemicals
Functional groups
Aromatic and nitro functional groups for incorporating into molecular structures for drug discovery
Versatility
Presence of the nitrile functional group makes it a valuable intermediate for the synthesis of other complex organic compounds
Value
Production of a wide range of useful products
Check Digit Verification of cas no
The CAS Registry Mumber 55233-09-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,2,3 and 3 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 55233-09:
(7*5)+(6*5)+(5*2)+(4*3)+(3*3)+(2*0)+(1*9)=105
105 % 10 = 5
So 55233-09-5 is a valid CAS Registry Number.
55233-09-5Relevant articles and documents
Oxidative nucleophilic substitution of hydrogen in nitroarenes
Makosza, Mieczyslaw,Stalinski, Krzysztof
, p. 2025 - 2031 (2007/10/03)
Carbanions of 2-phenylpropionitrile were found to add to nitroarenes in liquid ammonia to form σ(H) adducts, which were oxidized with KMnO4 to yield products of oxidative nucleophilic substitution of hydrogen (ONSH) in the position para to the nitro group. Treatment of the carbanion-nitroarene system with methyl iodide at -70°C indicated that the addition proceeds almost to completion. Thus, for the first time, the persistence of σ(H) adducts, formed between free anions and mononitroarenes, has been demonstrated. It was also shown that KMnO4, oxidizes σ(H) adducts to nitrobenzene faster than it does carbanions. This selective ONSH in the para positions of nitroarenes is a general process. However, some substituents hinder or inhibit the oxidation step.
