552331-00-7

Basic information

• Product Name: 4-IODOPYRIDIN-2-AMINE
• Synonyms: 4-IODOPYRIDIN-2-AMINE;2-Amino-4-iodopyridine;4-Iodo-2-aminopyridine;4-lodopyridin-2-aMine;2-PYRIDINAMINE,4-IODO-;-IODOPYRIDIN-2-AMINE
• CAS NO: 552331-00-7
• Molecular Formula: C₅H₅IN₂
• Molecular Weight: 220.01107
• EINECS: 145-896-5
• Product Categories: Pyridine series;Pyridines
• Mol File: 552331-00-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 163-164 °C
• Boiling Point: 309.378 °C at 760 mmHg
• Flash Point: 140.907 °C
• Appearance: /
• Density: 2.056 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.703
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 5.92±0.11(Predicted)
• CAS DataBase Reference: 4-IODOPYRIDIN-2-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-IODOPYRIDIN-2-AMINE(552331-00-7)
• EPA Substance Registry System: 4-IODOPYRIDIN-2-AMINE(552331-00-7)

Safety Data

• Hazardous Substances Data: 552331-00-7(Hazardous Substances Data)

Usage

General Description

4-Iodopyridin-2-amine is a chemical compound known for its role in organic synthesis as an intermediate. It belongs to the category of compounds known as pyridines and derivatives. It possesses a molecular formula of C5H5IN2. Its IUPAC name is 4-iodopyridin-2-ylamine. The chemical is often used to produce other compounds, particularly in pharmaceutical development. It is identified as a stable chemical but should be kept away from incompatible substances like strong oxidizing agents for safety reasons. It needs to be handled with caution and proper safety guidelines due to its toxic nature.

InChI:InChI=1/C5H5IN2/c6-4-1-2-8-5(7)3-4/h1-3H,(H2,7,8)

Upstream product

• 405939-28-8 (4-iodopyridin-2-yl)carbamic acid tert-butyl ester 
• 405939-79-9 4-iodo-2-nicotinic acid 
• 504-29-0 2-aminopyridine 
• 372-48-5 2-fluoropyridine 
• 22282-70-8 2-fluoro-4-iodopyridine 
• 60-35-5 acetamide 

Downstream Products

• 856169-98-7 N-(4-iodo-[2]pyridyl)-acetamide 
• 690258-25-4 7-iodo-[1,2,4]triazolo[1,5-a]pyridine 
• 1019648-91-9 N-(4-(2-oxo-5-phenyl-1,3-oxazolidin-3-yl)pyridin-2-yl)-N'-(pyridin-2-ylmethyl)urea 
• 1019648-49-7 N-benzyl-N'-(4-(2-oxopyrrolidin-1-yl)pyridin-2-yl)urea 
• 1019648-69-1 N-(4-(4-(4-methoxyphenyl)-2-oxopyrrolidin-1-yl)pyridin-2-yl)-N'-(pyridin-2-ylmethyl)urea 
• 1019648-68-0 bis(2,2,2-trichloroethyl)(4-(4-(4-methoxyphenyl)-2-oxopyrrolidin-1-yl)pyridin-2-yl)imidodicarbonate 
• 1019651-24-1 bis(2,2,2-trichloroethyl)(4-(2-oxo-5-phenyl-1,3-oxazolidin-3-yl)pyridin-2-yl)imidodicarbonate 
• 1019650-97-5 3-(2-aminopyridin-4-yl)-5-phenyl-1,3-oxazolidin-2-one 
• 1608144-25-7 2-amino-2-(5-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)furo[2,3-b]pyridin-2-yl)propane-1,3-diol 
• 94805-51-3 2-hydroxyisonicotinonitrile 
• 1608146-70-8 5-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-iodopyridin-2-ol 
• 1608146-72-0 tert-butyl N-(5-{5-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]furo[2,3-b]pyridin-2-yl}-2,2-dimethyl-1,3-dioxan-5-yl)carbamate 
• 42182-27-4 4-cyanopyridin-2-amine 

Relevant articles and documents

Synthesis and Optical Properties of the New Kaede Chromophore Analog

Abstract: A novel derivative of Kaede protein chromophore was synthesized. The compound showed the shift of absorption and emission maxima to the longwave region in comparison with the classical Kaede chromophore analog due to an increase in the conjugated π-system in the imidazolone fragment.

NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS

Provided are certain pyrazine derivatives (I) as SHP2 inhibitors which is shown as formula (I), their synthesis and their use for treating a SHP2 mediated disorder. More particularly, provided are fused heterocyclic derivatives useful as inhibitors of SHP

GSK-3BETA INHIBITOR

For the purpose of providing a GSK-3β inhibitor containing a 2-aminopyridine compound or a salt thereof or a prodrug thereof useful as an agent for the prophylaxis or treatment of a GSK-3β-related pathology or disease, the present invention provides a GSK-3β inhibitor containing a compound represented by the formula (IA): wherein each symbol is as defined in the specification. or a salt thereof or a prodrug thereof.