55238-64-7Relevant academic research and scientific papers
Enantioselective synthesis of tertiary thiols by intramolecular arylation of lithiated thiocarbamates
MacLellan, Paul,Clayden, Jonathan
supporting information; experimental part, p. 3395 - 3397 (2011/05/04)
Lithiation of N-aryl S-α-alkylbenzyl thiocarbamates leads to rearrangement with migration of the N-aryl ring to the anionic centre α to S, a process which generally proceeds with ca. 98% retention of stereochemistry and returns chiral benzylic tertiary thiols in high enantiomeric ratios.
Compounds and uses thereof for decreasing activity of hormone-sensitive lipase
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, (2008/06/13)
Use of compounds to inhibit hormone-sensitive lipase, pharmaceutical compositions comprising the compounds, methods of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may be useful in the treatment and/or prevention of medical disorders where a decreased activity of hormone-sensitive lipase is desirable.
