55239-18-4Relevant academic research and scientific papers
Enantioselective synthesis of tertiary thiols by intramolecular arylation of lithiated thiocarbamates
MacLellan, Paul,Clayden, Jonathan
supporting information; experimental part, p. 3395 - 3397 (2011/05/04)
Lithiation of N-aryl S-α-alkylbenzyl thiocarbamates leads to rearrangement with migration of the N-aryl ring to the anionic centre α to S, a process which generally proceeds with ca. 98% retention of stereochemistry and returns chiral benzylic tertiary thiols in high enantiomeric ratios.
