55243-81-7

Upstream product

• 55243-79-3 (6R)-3-[1,3]dioxolan-2-yl-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2ξ-carboxylic acid benzhydryl ester 
• 55243-80-6 (6R)-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2c,3-dicarboxylic acid 2-benzhydryl ester 3-(2-bromo-ethyl) ester 

Downstream Products

• 61225-19-2 (6R)-3-acetyl-7t-amino-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2ξ-carboxylic acid benzhydryl ester 
• 55243-82-8 (6R)-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2c,3-dicarboxylic acid 2-benzhydryl ester 

Relevant academic research and scientific papers

7-Acylamino-3-acyl-2(or 3)cephems

Intermediate C-3 1-hydroxyalkyl or 1-hydroxyarylalkyl cephems, prepared by reacting Grignard reagents at low temperature with 3-formyl-2-cephem compounds, are oxidized to the corresponding 7-acylamino-3-acyl-2(or 3)cephem-4-carboxylic acids and esters thereof, which are useful as antibiotics or as intermediates in preparing antibiotic substances.

3-(Substituted)carbonylamino cephem derivatives

7-Acylamino and 7-amino-3-(substituted)carbonylamino-3(or 2)-cephem-4-carboxylic acids and esters thereof, which are useful as antibiotics or as intermediates in preparing antibiotic substances respectively, are prepared from 7-acylamino-3-azidocarbonyl-2

3,4-Dicarboxycephalosporins and derivatives

7-Acylamino and 7-amino-3-carboxy-3-cephem-4-carboxylic acids and derivatives thereof, which are useful as antibiotics or as intermediates in preparing antibiotic substances, are prepared by an NBS oxidation of acetal derivatives of 3-formyl cephalosporin